In subject area:Biochemistry, Genetics and Molecular Biology Fibroblasts growth factor-7 (FGF-7) also known as keratinocyte growth factor (KGF) is 28-kDa protein with a 163 amino acid long polypeptide chain (Finch et al., 1989; From:Differentiation,2017 ...
CimaVax-EGF is a cancer vaccine composed of recombinant human epidermal growth factor (EGF) chemically conjugated to the Neisseria meningitidis outer protein P64k as an immunogenic protein carrier and containing Montanide ISA 51, a water-in-oil (w/o) emulsion with immunoadjuvant activity. ...
The factors that correlate with growth factor responsiveness depend on whether fold-change or absolute activity is considered the key biological variable, and they differ between ERK and AKT pathways. Conclusions Responses to growth factors are highly diverse across breast cancer cell lines, even ...
Definition 1 (BGSs): Let \({\bf{v}}^{\prime} \in {{\mathbb{R}}}^{n^{\prime} }\) be the vector of fluxes through the biochemical reactions that occur in a cell, in units of [mass][volume]−1[time]−1. Let \({\bf{v}}\in {{\mathbb{R}}}_{\ne 0}^{n}\), ...
Interestingly, despite the increasing level of lactate concentration and depletion in cell viability, the glucose level was remained detected in the group without any medium replacement in C/MR(−). This showed that instead of glucose starvation, lactate accumulation was the main limiting factor for...
Aberrant changes in levels of cytokines have far-reaching effects on the whole muscle as a result of altered regeneration. Elevated levels of pro-inflammatory cytokines interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α) have been found in muscles from individuals with CP and are linked...
On the other hand, to the best of our knowledge no systematic, longitudinal study has been conducted in Asian populations to conclude that early AR is a significant factor to differentiate for childhood obesity. For Western populations, for instance, Rolland-Cachera et al. found that children ...
-like growth factors (somatomedins), whichstimulategrowth by mediating the secretion ofgrowth hormonefrom thepituitary gland; epidermal growth factor, which stimulates the growth of epithelial cells;platelet-derived growth factor, which stimulates the growth ofmusclecells andconnective tissuecells; andnerve...
7). In contrast to the simple exponential Eq. (12), this model accounts for the mass-conservation condition linking substrate uptake to biomass formation through a constant yield factor, Y (Eq. 6), and the dependence of the specific growth rate on limiting substrate concentration: (16a)...
Generally, stress is defined as an extrinsic factor which affects the growth of the plant. These conditions challenge the plants’ growth and development and restrict their potential to reproduce and pass their genes to the next generation. In maximum scenarios, stress is measured in terms of ...