GROWTH FACTOR ACTIVITY ENHANCERPROBLEM TO BE SOLVED: To provide a medicine having low anticoagulant activity and excellent in growth factor activity enhancing effect.USUKI YASUTAKE臼杵 靖剛SEYAMA AKIKO瀬山 暁子KARIYA YUTAKA苅谷 豊
Improving the activation of GF receptors – controlling activity at the ‘destination’ end GFs are delivered to the wound milieu, to the microenvironment, to the cells; but the ‘real’ recipients are cell receptors. GFs are delivered to bind and activate their corresponding receptors on the cel...
Nerve growth factor (NGF) is a well characterized molecule required for the survival and differentiation of a variety of cell types both in the peripheral and central nervous system. Numerous studies published in recent years have demonstrated that NGF affects different functional activities of mature...
ECM is able to modulate wound repair, either directly by modulation of important aspects of cell behavior, such as migration, adhesion, proliferation, and survival, or indirectly by modulation of extracellular protease secretion, growth factor activity, and bioavailability. Keloids exhibit increased ...
However, scant information is available concerning the influence of traditional psychogenic or neurogenic stressors on the activity of circulating FGFs. Stressors can influence colony-stimulating factor and neuronal remodeling owing to effects on microglia and could thereby influence depressive-like behaviors...
1999. The mechanism of action of epidermal growth factor and transforming growth factor alpha on aromatase activity in granulosa cells from polycystic ovaries... A Misajon,P Hutchinson,N Lolatgis,... - 《Journal of Hellenic Studies》 被引量: 69发表: 2003年 The mechanism of action of epiderma...
Nerve growth factor (NGF) contributes to the progression of malignancy. However, the functional role and regulatory mechanisms of NGF in the development of neuroendocrine prostate cancer (NEPC) are unclear. Here, we show that an androgen-deprivation ther
The purity of each PeproTech growth factor lot is at least 98% as determined by SDS-PAGE and/or HPLC. In addition, each lot is tested for functionality and potency in cell-based assays. Lot-to-lot consistency of recombinant growth factors supports robust cell culture...
The cell growth-promoting activity was partially purified by a gel filtration column chromatography. The activity permeates through a ultrafiltration membrane (M.W. cut off: 500). Analyses of its chemical nature show that it is soluble in water, dimethyl sulfoxide or acetonitrile, insoluble in ...