In this work, the influence of common >N-CH 3 group present in the three free base, cationic and hydrochloride/bromide structures of scopolamine, heroin, morphine, cocaine and tropane alkaloids in gas and aqueous solution phases has been investigated theoretically by using B3LYP/6-31G* calculatio...
Multiple approaches are being investigated to find new covalent inhibitors such as: 1) cysteine reactivity mapping, 2) mapping cysteine ligandability, 3) and functional screening in phenotypic assays for electrophilic compounds Using fluorescent activity probes in proteomic screens; have broad useability ...
In the cracking fracture zone, only micro-fractures formed in the rock and the effects of late-stage hydrothermal activity are minimal; Li and Rb grades are typically not economical (Li et al., 2018, Jiang et al., 2022). Tin mineralization is largely restricted to quartz veins, with the ...
To consider group singing as a health-supporting activity in the same way as, for example, diet or exercise, it is important to understand the mechanism/s through which it achieves its effects. However, because of the complex and interdependent nature of these mechanisms, measuring isolated pheno...
Diurnal and gestational patterns of uterine activity in normal human pregnancy. Obstet Gynecol 1994;83:517 ± 523.Moore TR, Iams JD, Creasy RK, Burau KD, Davidson AL. Diurnal and gestational patterns of uterine activity in normal human pregnancy. Obstet Gynecol 1994; 83: 517-23....
conditions of neural degeneration because of accumulation with aging. tRFs have heterogenous functions with regulation of gene expression at multiple layers including regulation of mRNA processing and translation, inducing the activity of silencing of target genes, controlling cell growth and differentiation ...
Sixteen years ago,MacKenna Davidsonwas a runaway bride, and she never found the courage to face her jilted fiancé and family back in Burkitt, Texas. Then her sister’s nuptials set off the very chain of events she’s feared: a sense of homecoming she can’t untangle. ...
Oxidative Damage in Sporadic Colorectal Cancer: Molecular Mapping of Base Excision Repair Glycosylases in Colorectal Cancer Patients. International Journal of Molecular Sciences 2020; 21(7): 2473 doi: 10.3390/ijms21072473 72 Pauline Raoul, Marco Cintoni, Marta Palombaro, Luisa Basso, Emanuele Rinni...
We want specially to thank Total Congo for sponsoring of this study carried out in the frame of a mapping project in the Republic of the Congo. We thank also Georges Zaboukis and Francisco Serbeto Ibanez for the thin section production. We acknowledge Scott Elrick (ISGS) for the helpful dis...
Lolkema JS, Hoeve-Duurkens RH, Dijkstra DS, Robillard GT (1991) Mechanistic coupling of transport and phosphorylation activity by enzyme IImtl of the Escherichia coli phosphoenolpyruvate-dependent phosphotransferase system. Biochemistry 30:6716–6721 Article CAS PubMed Google Scholar Lolkema JS, Wartn...