The spread of GAS is aided by bacterial toxins and enzymes (eg, lipase, hyaluronidase, collagenase, streptokinase), interactions among organisms (synergistic infections), local tissue factors (eg, decreased blood and oxygen supply), and general host factors (eg, immunocompromised state, chronic ...
organisms. Although no strict separation can be made, group B streptococcus predominantly threatens neonates following vertical transmission from the birth canal of colonized parturients, their intestinal tract serving as an endogenous reservoir. As shown by history, group A streptococcus predominantly is...
Fully synthetic group A streptogramins tested for inhibitory activity against 20 strains of bacteria (see Extended Data Figs. 3, 4). Extended Data Fig. 3 Inhibitory activity against Gram-positive organisms. MIC values for selected analogues against an expanded panel of Gram-positive pathogens. So...
Of 6,694 throat cultures, 2,243 (34%) yielded B-hemolytic streptococci, 83 percent (1,783) of which were bacitracin-sensitive and presumptive group A organisms. A random selection of 279 of the 460 bacitracin-resistant streptococci yielded 56 group C, 42 group G, 35 group F, 2 group A...
angioneurotic or periorbital edema or unilateral interstitial edema in lungs.2 Patients with a history of prior exposure to streptokinase, infections with streptococci, and chronic allergic reactions are at risk for either by inducing an... Levent ZDEMR - 《Turkiye Klinikleri Journal of Medical ...
Mark A.Current Opinion in Infectious DiseasesKEROACK, M.A. Invasive group A streptococcal infection and streptococcal toxic shock syndrome. Curr Opin Infect Dis 4:621-6,1991.Keroack MA. Invasive group A Streptococcal infection and Strep- tococcal toxic shock syndrome. Curr Opin Infect Dis...
Streptococcus pyogenes (Group A Streptococcus, GAS) is a human-restricted pathogen that causes a wide variety of human diseases ranging from commonly mild superficial infections of the pharynx and skin to life-threatening invasive diseases such as necrotizing fasciitis1,2. GAS organisms are also ...
Although these organisms are normally found as oral bacterial flora, entry into the bloodstream can lead to fever and embolic events. Group C streptococci (S. equisimilis, S. zooepidemicus, S. equi, S. dysgalactiae) primarily cause diseases of animals and pose little threat to immunocompetent ...
THE virulence of organisms can be enhanced by a variety of substances, mainly of carbohydrate nature (see review by Olitzki1). Current interest centres on mucin, which was found by Smith and his co-workers2–4 to owe its activity to the synergic action of three factors—viscosity, a partic...
Group C streptococci (GCS) and group G beta-haemolytic streptococci (GGS) have caused well-documented epidemics of acute pharyngitis in children, but the importance of these organisms in causing endemic or sporadic pharyngitis is uncertain. The heterogeneity of GCS and GGS may obscure the role of...