L. Gads (Grb2-related adaptor downstream of Shc) is required for BCR-ABL-mediated lymphoid leukemia. Leukemia 27, 1666-1676 (2013).Gillis,L.C.,Berry,etc.Gads (Grb2-related adaptor downstream of Shc) is required
In this study, we explore the expression and function of the Grb2-related protein of the lymphoid system (GrpL)/Grb2-related adaptor downstream of Shc adapter protein in human B cells. GrpL is expressed in naive B cells and is down-regulated following B cell Ag receptor ligation. By ...
These data suggest that GADS mediates lymphoid disease downstream of BCR-ABL through the recruitment of specific signaling intermediates.LCGillisDMBerryMDMindenCEBSCO_AspLeukemiaGillis LC, Berry DM, Minden MD, McGlade CJ & Barber DL (2013) Gads (Grb2-related adaptor downstream of Shc) is ...