Enzymes are crucial in numerous biological processes, with the Enzyme Commission (EC) number being a commonly used method for defining enzyme function. However, current EC number prediction technologies have not fully recognized the importance of enzyme active sites and structural characteristics. Here,...
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In metabolite-centred metabolic networks, two metabolites (nodes), u and v, are connected by a directed edge from u to v if there is an enzyme that catalyse a reaction having u as one of its substrates and v as one of its products. In enzyme-centred metabolic networks, two enzymes (...
This is achieved by comparing representation similarities between a query protein and all labels, thanks to the aligned representation space of protein sequences and label descriptions in ProtST.We demonstrate on zero-shot subcellular localization prediction and zero-shot reaction classification with Pro...
Based on our findings from the signal flow graphs, we have presented a heuristic method for determining the flux control coefficients directly from the reaction sequence of the pathway, without drawing a signal flow graph. The present analysis applies to metabolic pathways in a steady state....
But this is not always so and the program therefore allows to intercalate additional reactions, which were not part of the initial set of seeds. The underlying algorithm is a single linkage clustering over the metabolic graph, with the distance metric between two reaction clusters being the ...
As used herein, the term “real time” refers to taking multiple measurements during a reaction or interaction as opposed to making a single measurement at the end of the reaction, or at a specified time point. Real time measurements are often used to quantitate the amount of a component in...
Protein-Protein Interactions (PPIs) are fundamental means of functions and signalings in biological systems. The massive growth in demand and cost associated with experimental PPI studies calls for computational tools for automated prediction and underst
Understanding protein function is pivotal in comprehending the intricate mechanisms that underlie many crucial biological activities, with far-reaching implications in the fields of medicine, biotechnology, and drug development. However, more than 200 mi
An experiment was carried out to investigate the effect of pH on enzyme action. The graph shows the results. What are the labels for the x-axis and the y-axis? A. pH and rate of reaction B. pH and time C. rate of reaction and pH D. time and pH 如何将EXCEL生成题库...