Data on demographic characteristics, primary diagnosis, comorbidity, number of indwelling devices, previous microbial isolates and current antibiotics were cross-tabulated according to the presence and type of Gram(+) pathogens isolated. For the identified most likely risk factors, separate contingency ...
positive-specific fluorescent probe,we demonstrate two-color imaging of Gram-positive and Gram-negative bacteria in various kinds living microbiotas,including mouse gut,human oral,soil,and crude oil microbiotas,with high selectivity and coverage.Finally,a pilot use of the probes in staining bacteria ...
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The BCID-GN panel enabled earlier time to optimal treatment of highly resistant bacteria as well as multiple opportunities for narrowing gram negative spectrum and a higher degree of certainty in cessation of broad-spectrum gram-positive antibiotics DISCLOSURES. Todd P. McCarty, MD, Cidara (Grant/...
Fluoroquinolone antibiotics: properties of the class and individual agents. The development of future agents with better gram-positive activity, improved gram-negative coverage, and activity against unusual pathogens such as Chlamydia ... C Stratton - 《Clinical Therapeutics》 被引量: 73发表: 1992年 ...
As the prevalence of resistance to some commonly prescribed antibiotics increases, particularly among gram-negative pathogens in critically ill patients, empiric combination therapy has become very important in clinical practice. As a result, the likelihood of selecting adequate empiric coverage by using ...
Virginiamycin acetyltransferase (Vat) enzymes are resistance proteins that provide protection against streptogramins2, potent antibiotics against Gram-positive bacteria that inhibit the bacterial ribosome3. Owing to the challenge of selectively modifying the chemically complex, 23-membered macrocyclic scaffold...
There was no significant difference in coverage rates of initial antibiotic therapies between the groups (86.4% [89 of 103] vs 92.2% [95 of 103]; P = .18). Escalation of antibiotics according to culture results was performed in 7 patients (6.8%) in the Gram stain–guided group and...
Combinations of antibiotics such as a β-lactam and an aminoglycoside are used for multiple reasons: to afford coverage in the event the pathogen proves resistant to one of the agents, to afford a synergistic activity thus improving and prolonging the serum bactericidal activity, and to reduce ...
To show the positive impact of using the adjunct therapy, the ozone and antibiotic treatment was tested on strains of P. aeruginosa and E. coli, G − ve bacteria commonly found in SSTIs. For these tests, two antibiotics commonly used to treat G + ve bacteria, vancomycin and ...