The dose—response relation of many agonists yield sigmoidal ( S -shaped) curves when the response is plotted against the logarithm of the dose (see Figure 8.1). There is no generally accepted theory that explains the shape of such curves; yet, we find that such curves are often ...
...暴露特征,效应、反应(response)、剂量- 量反应关系(graded dose-response relationship)和剂量-质反应关系(quantal dos…www.docin.com|基于3个网页 2. 剂量一量反应关系 三、剂量一量反应关系和剂量一质反应关系 剂量一量反应关系(graded dose-response relationship)表示化学物质的剂量与个体 …www.docin.com...
This model describes dose-response curves in terms of the magnitude of the peak response, the dose of mitogen that elicits the peak and an estimate of the range of mitogen doses which induce a response. Responses to ConA were described by the model more precisely than those to PHA. Further...
To examine the effect of a relatively low dose of creatine on skeletal muscle metabolism and oxygen supply in a group of training athletes.31P magnetic res... CH Thompson,GJ Kemp,AL Sanderson,... - 《British Journal of Sports Medicine》 被引量: 217发表: 1996年 Testing and implementing coc...
Hopman, WPM, Kerstens, PJSM, Jansen, JBMJ, Rosenbusch, G, Lamers, CBHW (1985) The effect of graded physiologic doses of cholecystokinin on gallbladder contraction measured by ultrasonography; determination of treshold, dose-response relationships and comparison with intraduodenal bilirubin output...
(250 μM). This represents a maximal induction ratio of 74-fold. In the range of 6.5 to 74 μM vanillate, the dose-response curve was essentially linear (R2= 0.994), indicating that PV10allows graded gene expression, rather than showing switch-like behavior. To follow induction ...
We administered nitroglycerin intravenously to 10 patients with alcoholic cirrhosis, beginning at 10 μg/min and doubling the dose every 10 min thereafter until mean arterial pressure fell 10–15 mmHg. We compared the response to that of 10 patients receiving a control infusion. The median in...
On Cross-over Tests with a Graded Response: Statistical Analyses and the Concept of the "Log-dose Difference Response-Difference Line". 喜欢 0 阅读量: 18 作者: C Rerup 摘要: One specimen of Eumpos perotis was collected at Sierra de Juarez, Baja California, Mexico. This record represents ...
Dose-response relation between physical activity and fitness: even a little is good; more is better. The concept of dose is important in clinical medicine. In the pharmacological treatment of many conditions, physicians typically start with a dose of a dru... IM Lee - 《Jama the Journal of...
The plasma free amino acid dose-response technique: a proposed methodology for determining lysine relative bioavailability of rumen-protected lysine supplements. J Dairy Sci 2017; 100: 9585-9601.. Google Scholar [52] Wray-Cahen D, Metcalf JA, Backwell FR, Bequette BJ, Brown DS, Sutton JD,...