(2007) PSA failure following definitive treatment of prostate cancer having biopsy Gleason score 7 with tertiary Grade 5. JAMA 298: 1533–1538 Combined therapy improves survival in advanced-stage endometrial cancer Early-stage endometrial cancer has an excel- lent prognosis; however, the survival ...
Patient summary:For patients with grade 5 prostate cancer, we found differences in cancer-specific death rates according to the pattern of abnormal cells in the prostate, called the Gleason score. The highest death rate was found for a Gleason pattern score of 5 + 5, followed by Gleason 5 ...
While checkpoint therapy has emerged as a proven strategy for cancer immunotherapy, its effectiveness in brain tumors, including glioblastoma, has been limited156. In a phase III clinical trial for patients with recurrent GBM, there was no discernible improvement in survival benefit attributed to ...
The 5-year relative survival rate of advanced-stage patients is only 29%, while that of early-stage patients is 92% [5]. Therefore, it is essential to explore new biomarkers for HGSOC carcinogenesis and prognosis, as well as alternative therapeutic targets. ETS variant transcription factor 5 ...
Patel SA, Baumann B, Michalski J et al (2023) Association of brachytherapy boost with overall survival for Gleason 9–10 prostate cancer: the impact of primary versus secondary pattern 5. Brachytherapy 22:310–316 ArticlePubMedGoogle Scholar ...
While these types of cancers are relatively rare, patient prognosis is quite poor, with an average 2-year overall survival of only 20% [5], despite multimodal treatment regimens consisting of surgery, radiation therapy, and chemotherapy [6, 7]. Tumor location or disease progression can further ...
Most patients with HGSOC have advanced disease at the time of diagnosis, and their long-term survival rates are low [5, 6]. The International Federation of Gynecology and Obstetrics (FIGO) ovarian cancer staging system [7] does not include substaging of lymph nodes, except as a distant ...
est en effet passée de 6–7 ans avec une simple biopsie initiale [4]à 13–15 ans lors de résection précoce, comme mis en évidence dans l’expérience française basée sur plus de mille cas, soit la plus importante série de gliomes de grade II OMS jamais rapportée [5], [6...
Moreover, the survival analysis of the identified markers revealed increased expression of these markers in the transcriptome leads to poor survival in all six proteins (Supplementary Fig. 5). We believe that the efficacy of these new biomarkers, exhibiting high performance in both tissue and serum...
The clinicopathological parameters such as residual tumor, grade, the International Federation of Gynecology and Obstetrics (FIGO) score are often used to predict the survival of ovarian cancer patients, but the 5-year survival of high grade serous ovarian cancer (HGSOC) still remains around 30%....