论著• 方法学研究 2011, 11(4): 437 445 中国循证医学杂志 ～ GRADE 指南:Ⅰ. 导论—— GRADE 证据概要表 和结果总结表△ GRADE Guidelines: 1. Introduction to GRADE Evidence Proi les and Summary of Findings Tables△ Gordon Guyatt ,Andrew D. Oxman ,Elie Akl ,Regina Kunz ,Gunn Vist ,Jan ...
因此该分析中 602 例不符合 COPD 患者的系统评价,住院天数缩短的 CI 下限 较严格的 OIS 标准,应考虑因不精确性而降低证据 值为 0.65 天。如果效应值真这么小,我们仍会推荐 质量级别。 服用皮质类固醇吗? 注意,我们是否因不精确性而降低证据质量级 指南(与系统评价截然相反)需考虑整体情况 别取决于作者希望检测...
Objective: To determine the association between the Malay version of COPD Assessment Test (CAT) with severity of airflow limitation based on The Global Initiative for Chronic Obstructive Lung Disease (GOLD) grade, cardiovascular co-morbidities and frequency of acute Chronic Obstructive Pulmonary Disease...
Chronic diseases and conditions such as HIV/AIDS, cancer, and chronic obstructive pulmonary disease (COPD) have long-lasting effects and costs and have pro... the state of the science and to make recommendations for measuring patient-centric outcomes in interventions for motor improvement in the ...
Diagnosis, prevalence, and clinical impact of sarcopenia in COPD: a systematic review and meta-analysis. J Cachexia Sarcopenia Muscle. 2020;11:1164–76. Article PubMed PubMed Central Google Scholar Rolland Y, Czerwinski S, Abellan VKG, Morley JE, Cesari M, Onder G, et al. Sarcopenia: ...
4 The WHO has defined a minimum set of intervention for the diagnosis of COPD in primary care.6 The prevalence of COPD in adults aged over 40 years ranges between 2.48 and 9.5%, based on telephone or database surveys conducted in Taiwan.7, 8, 9 However, the prevalence of COPD may be...
2) moderate: further research is recommended to increase confidence in the estimate of effect and may change the estimate; 3) low: further research is very likely to change estimates and is highly recommended; and 4) very low: any estimate of effect is very uncertain and new research is nec...
MRC grade of a healthy population is not usually reported and assumed to be 1, however this may not be accurate. The characteristics of COPD individuals with MRC grade 2 aren't well defined and furthermore it has not been established if physical activity is impaired, compared to a similar ...
CpG methylation is a consequence of increased blood CRP levels. Mediation analysis reveals obesity and smoking as important underlying driving factors for changed CpG methylation. Finally, we find that an activated CpG signature significantly increases the risk for cardiometabolic diseases and COPD. ...
VII, which is down in low-dose and high in high-dose. With closer inspection,Hdac2andHdac4are included within this clusters.Hdac2is considered to be crucial to the LPS inflammatory response while also mediating it, and decreasedHdac2levels have been found in COPD patients113,114,115.Hdac4...