Monoamine oxidase A (MAO-A) , a mitochondrial enzyme that degrades monoaminesincluding neurotransmitters, is highly expressed in basal cells of the normal humanprostatic epithelium and in poorly differentiated (Gleason grades 4 and 5), aggressiveprostate cancer (PCa). Clorgyline, an MAO-A ...
Furthermore, p53 can sensitise cancer cells by upregulating their FAS receptor, to the apoptotic attack by cytotoxic T cells or NK-cells. These would recognise the cancer cell by binding its FAS receptor to the FASLG expressed on their membrane and hence induce apoptosis in a cancer cell43. ...
Lerner-Ellis J, Alvandi Z, Bernardini MQ, MacKay HJ, Mojtahedi G, Tone AA, Massey C, Clarke BA (2014) Performance characteristics of screening strategies for Lynch syndrome in unselected women with newly diagnosed endometrial cancer who have undergone universal germline mutation testing: Lynch Syndro...
CHO cells 内毒素(Endotoxin level) Please contact with the lab for this information. 生物活性 产品描述(Description) Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer). ...
Smoking Is a Risk Factor for Cervical Intraepithelial Neoplasia Grade 3 among Oncogenic Human Papillomavirus DNA–Positive Women with Equivocal or Mildly A... BACKGROUND: Smoking is a potential risk factor for cervical cancer and its immediate precursor, cervical intraepithelial neoplasia grade 3 (CIN...
The patient had a remote history of tubal ligation and no known personal or family history of breast or gynecologic cancer. She initially presented with an abnormal Pap smear, and, on a subsequent endometrial curettage, detached fragments of high-grade adenocarcinoma were identified. Upon ...
We describe the generation of monocyte-derived dendritic cells (MoDC) from leukapheresis products using the CliniMACS system from Miltenyi Biotec. In a clinical setting, the method turned out to be feasible for the generation of clinical-grade MoDC from patients with metastatic renal-cell carcinoma...
TMPRSS2-ERG Fusion Gene Expression in Prostate Tumor Cells and Its Clinical and Biological Significance in Prostate Cancer Progression. J Cancer Sci Ther. 2012;4(4):94-101.PubMedGoogle ScholarCrossref 48. Hagen RM, Adamo P, Karamat S, et al. Quantitative analysis of ERG expression and ...
Our analysis supports the hypothesis that bivalent marks are associated with epigenetic silencing in ovarian cancer. However it also suggests that additional tumour specific bivalent marks, to those known in ES cells, are present in tumours and may potentially influence the subsequent development of ...
CHO cells 内毒素(Endotoxin level) Please contact with the lab for this information. 生物活性 产品描述(Description) Tremelimumab is under investigation for the treatment of Mesothelioma, Liver Cancer, Liver Neoplasms, Liver Cell Caricinoma, and HepatoCellular Carcinoma. Tremelimumab has been investigated...