MucositisPancytopeniaALLAntimetabolite drugs are rarely associated with grade 3 or 4 mucositis. However specific side effects such as bone marrow suppression, pancytopenia, hospitalization, high cost limit the use of intravenous methotrexate. Here we report a case of 25-year-old girl patient with ...
However, when associated with M pneumoniae infection, mucositis tends to be more prominent; other skin involvement includes predominantly acral or extremity lesions. These dermatologic phenomena have been acknowledged as a distinct entity and termed as “M pneumoniae-induced rash and mucositis” (MIRM)...
Two-year OS was 30% and PFS was 20% and 27% of the patients had no evi- dence of recurrent disease at 2 years. Mucositis and oral pain were the most common grade 3 adverse events, fol- lowed by fatigue, bone necrosis in 3 patients and soft tis- sue necrosis in one. Based on ...
Of note, 2 grade 3 cases of mucositis and neutropenia were observed and a grade 4 elevation of liver enzymes was seen in another case, with 2 patients dying due to disease progression during treatment. Still, daily use of this drug provided physicians with an alternative treatment for patien...
Additional analysis showed that AEs of special interest (AESIs)—including oral mucositis or stomatitis, ocular surface toxicity, and adjudicated drug-related interstitial lung disease (ILD)—were found to be low grade and manageable in the dato-DX...
Other categories are cutaneous reaction, 10 (10/0); first dose reaction, 3 (3/0); pulmonary obstruction, 3(3/0); abdominal pain, 2(1/1); prolonged cytopenia, 2(1/1); fever, 1 (1/0); nausea, 1 (0/1); psychiatric depression, 1 (1/0); microangiopathy, 1 (1/0); mucositis...
Two-year OS was 30% and PFS was 20% and 27% of the patients had no evidence of recurrent disease at 2 years. Mucositis and oral pain were the most common grade 3 adverse events, followed by fatigue, bone necrosis in 3 patients and soft tissue necrosis in one. Based on these ...
3,3 '-dimethyl-biphenyl diisocyanate; 3, 3' -dimethyl-biphenyl diisocyanate; TODI [CAS number] [Molecular formula] C16H12N2O2 [Molecular weight] 264.28 [density] 1.156 (80ºC) [melting point] 70 [boiling point] 195 ~ 197 (667 pa) [flash point] 214 [Toxi...
Oral Dis. 2007;13:170 -176.Bonan PRF, Kaminagakura E, Pires FR, Vargas PA, De Almeida OP. Histomorphometry and immuno- histochemical features of grade I (WHO) oral radiomucositis. Oral Dis 2007; 2:170-6. http://dx.doi.org/ 10.1111/j.1601-0825.2006.01254.x...
Topical dexamethasone rinses or topical corticosteroids may be employed for commonly seen mucositis and stomatitis [37]. Additionally, episodes of interstitial pneumonitis have been documented to easily resolve with the use of oral steroids [25]. Other side effects may be managed supportively, including...