Isolate highly purified mouse MDSCs (CD11b+Gr1+) from splenocytes, bone marrow, or peripheral blood in as little as 18 minutes with EasySep™.
(MDSC) and play a major role in regulation of inflammation in many pathological conditions. Although MDSC have been described primarily in cancer their function in tuberculosis remains unknown. During M. tuberculosis infection it is crucial to understand the function of cells involved in the ...
Myeloid derived suppressor cells (MDSC) are a CD11b(+)Gr1(+)population in mice that can be separated into granulocytic (g-MDSC) and monocytic (m-MDSC) subtypes based on their expression of Ly6G and Ly6C.Charles...
My research aim is to investigate the response of the immune system after immune-therapy. The experiment was performed to show Gr1 + MDSC of brain tumor-bearing mice in treated mice. Brilliant Violet 521™ anti-mouse Gr1 has been chosen because is a bright antibody. ...
Gr1(int)CD11b(+) cells are called myeloid-derived suppressor cells (MDSC) and play a major role in regulation of inflammation in many pathological conditions. Although MDSC have been described primarily in cancer their function in tuberculosis remains unknown. During M. tuberculosis infection it is...
Tumor-associated factors are related to increased accumulation of CD11b(+) Gr1(+) myeloid-derived suppressor cells (MDSCs). However, the exact mechanism of how genetic factors control the expansion of MDSCs in tumor-bearing hosts remains elusive. Herein, we found that tumor-associated MDSCs ...
CD11b+ Gr1dim cells were transferred to ZyA-treated SKG mice.MDSCs, Th17 cells, and group 1 and 3 innate lymphoid cells (ILC1s and ILC3s) were increased in the lungs; the proportion of these cells varied with ILD severity. In this process, we found that a unique cell population, CD...
目的 探讨地塞米松诱导骨髓来源抑制细胞(MDSCs)在同种异系小鼠皮肤移植模型中的表达及免疫负调节作用。方法 以雌性BALB/c小鼠皮肤为供体,雄性C57BL/6小鼠为受体,建立... 廖炯博 - 《上海交通大学学报(医学版)》 被引量: 0发表: 2014年 RNA m6A修饰调控MDSC的分化及其免疫抑制功能 利用RT-PCR检测MDSC免疫抑制...
MDSC 髓系来源抑制性细胞 Nos2 Induced nitricoxide synthase 诱导型一氧化氮合酶 ArgI Arginase 1 精氨酸酶 I FITC Fluorescin isothiocyanate 异硫酸酯荧光素 TAM Tumor associated macrophage 肿瘤相关巨噬细胞 Phycoerythrin PE 藻红蛋白 IL-12 Interleukin-12 白细胞介素-12 ...
Interestingly, Gr1hiCD11b+, as well as Gr1lowCD11b+, cells have been characterized as granulocytic and monocytic myeloid derived suppressor cells (MDSCs), respectively. Hence, we hypothesized that - Gr1hiCD11b+ cells suppress B cell activation and differentiation and protect against lupus-like ...