Expanding Clinical Spectrum of Anti-GQ1b Antibody Syndrome A Review. JAMA Neurol.2024 Jul 1;81(7):762-770. END 转自:神经科的那些事
抗GQ1b抗体综合征(anti-GQ1b antibody syndrome)是由空肠弯曲菌、流感嗜血杆菌等微生物感染,诱导产生抗GQ1b抗体,随后GQ1b抗体与动眼、滑车、展神经、肢体的肌梭和脑干的GQ1b抗原结合,从而导致中枢和周围神经系统病变的自身免疫性连续性疾病谱。 历史由来: 1938年,...
1.2 方法 使用中英文检索词“抗GQ1b抗体综合征”、“Bickerstaff脑干脑炎”、“癫痫”、“抽搐”、“GQ1b”、“anti-GQ1b antibody syndrome”、“Bickerstaff brainstem encephalitis”、“epilepsy”、“seizure”,检索数据库PubMed、Web o...
Panda S, Tripathi M. Anti-GQ1b antibody syndrome: clinical and immunological range. J Neurol Neurosurg Psychiatry 2002;72(3):418-9. 15. Snyder LA, Rismondo V, Miller NR. The Fisher variant of Guillain-Barre syndrome (Fisher syndrome). J Neuroophtalmol 2009;29(4):312-24....
抗GQ1b抗体综合征(anti-GQ1b antibody syndrome)是由空肠弯曲菌、流感嗜血杆菌等微生物感染,诱导产生抗GQ1b抗体,随后GQ1b抗体与动眼、滑车、展神经、肢体的肌梭和脑干的GQ1b抗原结合,从而导致中枢和周围神经系统病变的自身免疫性连续性疾病谱。抗GQ1b抗体综合征的特征性表现为眼外肌麻痹、共济失调和意识障碍。其由Odaka...
Barrésyndrome，GBS），Bickerstaff’s脑干脑炎 （Bickerstaff’s brainstem encephalitis，BBE）和急性 眼肌麻痹[2]。该病多为单相病程，预后较好，但有部 分患者可出现复发。复发性抗GQ1b抗体综合征在 文献中少有报道，如何预防复发更是鲜有提及。本 文报道1例复发性抗GQ1b抗体综合征，伴血清抗 GQ1b及抗GT1a抗体...
Anti-G Q1b antibodyThe Guillain-Barre syndrome (GBS) is sometimes associated with autoantibodies to gangliosides. Chiba et al. and Yuki et al. found a frequent association of Fisher syndrome (FS) and anti-Gganglioside antibodies. We report on a 15-year-old boy with FS which evolved into ...
A case report and literature review of anti-GQ1B antibody syndrome with acute vestibular syndrome as the first manifestation 在线阅读 下载PDF 引用 收藏 分享 摘要 目的 分析以急性前庭综合征为首发表现的抗GQ1b抗体综合征的临床特点及眼部运动表现。方法 报道1例以急性前庭综合征为首发表现的抗GQ1b抗体综合征...
ELISA = enzyme‐linked immunoaborbent assay; GBS = Guillain‐Barré syndrome; IgG = immunoglobulin G; IgM = immunoglobulin M; IVIg = intravenous immunoglobulin; MFS = Miller Fisher syndrome; mAb = monoclonal antibody; PBS = phosphate‐buffered saline; OND = other neurological disease; TGM2 = ...
Anti-GQ1b IgG antibody syndrome comprises a wide range of diseases presenting with ophthalmoplegia and ataxia. Anti-GQ1b antibodies have been strongly associated in the literature with Miller Fisher Syndrome, with acute ophthalmoplegia associated with Guillain-Barr茅 syndrome, and with isolated ophthalm...