The Wnt signaling pathway is crucial for tissue morphogenesis, participating in cellular behavior changes, notably during the process of convergent-extension. Interactions between Wnt-secreting and receiving cells during convergent-extension remain elusive. We investigated the role and genetic interactions of...
To test our idea, we generated GPC4-overexpressed plasmids to examine the importance of GPC4 in CD36-mediated tumor-suppressive function. Consistent with previous work, we firstly found GPC4 overexpression could lead to a higher upregulation of β-catenin after Wnt3a treatment than negative contro...
Distinct requirements of wls, wnt9a, wnt5b and gpc4 in regulating chondrocyte maturation and timing of endochondral ossification.doi:10.1016/j.ydbio.2016.11.016Irving T.C. LingLucie RochardEric C. LiaoAcademic Press