GPBAR1重组蛋白:功能结构域详解—艾普蒂生物 GPBAR1(G Protein-coupled Bile Acid Receptor 1),也称为TGR5(Takeda G-protein-receptor 5),是G蛋白偶联受体(GPCR)家族的一员。作为胆汁酸受体,GPBAR1在代谢调控、炎症反应和能量平衡中发挥重要作用。重组GPBAR1蛋白通过基因工程技术在体外表达和纯化,对于研究其...
TGR5 (Gpbar1, M-BAR) is a Gs protein-coupled, cell surface receptor responsive to bile acids as well as various steroid hormones. Ligand binding to TGR5 activates adenylate cyclase, triggers an elevation of intracellular cyclic AMP (cAMP) levels and activates further downstream signaling pathways...
抗体名称 Anti-GPBAR1 Antibody 指标别名 GPBAR1;TGR5;G-protein coupled bile acid receptor 1;G-protein coupled receptor GPCR19;hGPCR19;Membrane-type receptor for bile acids;M-BAR;hBG37;BG37 克隆性 Polyclonal 检验物种 mouse,rat 应用范围 WB 基因名称 GPBAR1 抗体来源 Rabbit 抗体类型 IgG 免疫原 A...
指标别名GPBAR1;TGR5;G-protein coupled bile acid receptor 1;G-protein coupled receptor GPCR19;hGPCR19;Membrane-type receptor for bile acids;M-BAR;hBG37;BG37 克隆性Polyclonal 检验物种human,mouse,rat 应用范围WB 基因名称GPBAR1 抗体来源Rabbit ...
基因又名: BG37; GPCR19; GPR131; M-BAR; TGR5 Gene ID: 151306 种属 Homo sapiens 基因DNA序列编号: NM_001077191.2 基因DNA描述 Homo sapiens G protein-coupled bile acid receptor 1 (GPBAR1), transcript variant 1, mRNA DNA编码区: atgacgcccaacagcactggcgaggtgcccagccccattcccaagggggctttggggctc ...
提供的GPBAR1 多克隆抗体为兔来源的多抗。GPBAR1 又称BG37|GPCR|GPCR19|GPR131|M-BAR|MGC40597|TGR5,其基因全名为G protein-coupled bile acid receptor 1,蛋白号为Q8TDU6。 应用类型 IHC-P 免疫原 A synthetic peptide corresponding to 19 amino acid at C-terminus of human GPBAR1。
Gpbar1(TGR5),一个膜结合型胆汁酸受体,众所周知,其在能量平衡和糖代谢调节中发挥作用。在体外TGR5也显 示出较强的巨噬细胞反应衰减,但TGR5在炎症反应中的生理作用,以及其作用机制,还是未知的。在这里,我们证实, TGR5是一种核转录因子-κB(NF-κB)介导的炎症反向调节因子。TGR5活化可抑制B细胞抑制剂,α(IκBα...
HEK293 human embryonic kidney cell line transfected with human TGR5/GPBAR1 and eGFP was stained with either (A) Mouse Anti-Human TGR5/GPBAR1 PE-conjugated Monoclonal Antibody (Catalog # FAB4286P) or (B) Mouse IgG2BPhycoerythrin Isotype Control (Catalog # IC0041P). View our protocol for Stai...
基因基本信息 基因简称(symbol) GPBAR1[HGNC][GeneCards][NCBI] 基因种类(locus group) protein-coding gene 同源简称(alias symbol) BG37|GPCR|TGR5|M-BAR|GPCR19|GPR131|MGC40597 基因家族代码(gene_family_id) 933[HGNC][GenScript] omim代码