All chemicals were of American Chemical Society reagent grade and were purchased from SigmaAldrich (Deisenhofen, Germany) unless stated otherwise. Phycoerythrin (PE) conjugated SR-AI antibodies and biotinylated goat anti-human SREC-I antibodies were purchased from R&D Systems (Minneapolis, MN). Unbio...
Of note, two isoforms of GP2, termed alpha (GP2a) and beta (GP2b), both expressed at equal levels in the pancreas, were described.[19; 27] The two variants of GP2 are produced in humans due to alternative splicing. Besides the large form of GP2, containing 537 amino acids and termed...
Download: Download full-size image Fig. 5. CASV and GGV infectivity requires an acidic endosomal environment. (a) Chemical inhibitors of endosomal acidification decrease CASV and GGV production. Quantification of supernatant viral RNA levels following treatment with indicated drugs. The mean and standa...
While the furanindoline pharmacophore is unsuitable for tumour-selective therapy, the selective CYP2W1 bioactivation of the IPChaTrm27ac2e6utiscualgs g20e1s7t, 1t0h,a9t7 this duocarmycin analogue could be used as chemical tool to probe CY1P52oWf 310 functional activity. PharmFFaicigeguuutri...