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gp350 and derived from the hybridoma cell line 72A1 was produced in 1980, and in the past decades it has been shown to neutralize EBV infection of B cells in vitro, prevent development of EBV-positive tumors in xenograft mouse models, and provide some passive immunization effects in patients...
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Thus, taking the unique mechanism of gp120-binding protein and gp41- binding antibody in combination, we see that the resultant synergism promotes more effective inhibitory activity against different HIV-1 strains than either the gp120-binding protein or the gp41-binding antibody used alone. More...