Cancer patients frequently turn to general practitioners (GPs) for work-related advice and support. Few studies in Scotland have explored the role of GPs in advising cancer patients about work, despite the recommendation that employment should be discussed with cancer patients in primary care.Sarah ...
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PI3K/AKT is a vital signaling pathway in humans. Recently, several PI3K/AKT inhibitors were reported to have the ability to reverse cancer multidrug resistance (MDR); however, specific targets in the PI3K/AKT pathways and the mechanisms associated with M
Discussion Development of drug resistance is a recurring problem in treating ER+ breast cancer patients even with the recently introduced aromatase inhibitors [8-9; 36-40]. Overexpression of several growth factors and growth factor receptors overexpression and cross talk with ER have been described as...
Discussion Development of drug resistance is a recurring problem in treating ER+ breast cancer patients even with the recently introduced aromatase inhibitors [8-9; 36-40]. Overexpression of several growth factors and growth factor receptors overexpression and cross talk with ER have been described as...
a prospective audit br j cancer, 100 (2009), pp. 1867-1872 google scholar 8 m roland, b bewley boneline: evaluation of an initiative to improve communication between specialists and general practitioners j public health med, 14 (1992), pp. 307-309 google scholar 9 dm berwick, tw nolan,...
much better understanding of the causality of CRC are founded by incorporating epidemiology and genetic/epigenetic on CRC etiology. This method might be able to significantly lower the burden of CRC in North Africa. Cervical cancer (CC) is a very common gynecological malignancy globally. Some custom...
A common classification framework for neuroendocrine neoplasms: an Interna- tional Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal. Mod Pathol. 2018;31:1770–86. 4. Finn RS. Development of molecularly targeted therapies in hepatocellular carci- noma...
4. Discussion In the present study, we investigated the functional and clinical relevance of mgp96 in liver cancer. We observed that elevated mgp96 expression is significantly correlated with tumor metastasis, a shorter DFS, and poor prognosis in liver cancer patients. Using proteomic profiling of...
Jun Yotoka (National Cancer Center Research Institute, Japan). pcDNA3-gp78ΔVIM was created by site-directed mutagenesis to introduce a stop codon that truncates the C-terminal 30 amino acids (VIM). To make recombinant GST-VIM, cDNA encoding the VIM of human gp78 was cloned into the ...