Although the randomized controlled trial (RCT) is the best study design for dealing with questions of intervention, RCTs under low-prevalence conditions are extremely challenging because of the limited number of patients, the variable phenotypic expression, and the long course ...
DO: Policymakers often think about improvement in terms of identifying what works in general, based upon randomized control trials (RCT), often seen as a gold standard in certain fields. This prototypical approach to research, however, may not always be possible and/or ethical in educational set...
Findings lose padlocks for design (if there is no comparison group then studies cannot receive any padlocks); the statistical power (which comes from sample size); the imbalance between groups; and the number of pupils that drop out of the study. There are other potential threats to ...
I only used one set of parameter values, a single sample size, a single covariate, a strictly linear model, and only two missing data mechanisms. But, at the least, it should tell us that DVA is a strong contender for dealing with missing baseline covariate values in RCTs. R Code for...
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PubMed, the Cochrane Library and the databases of the Centre for Reviews and Dissemination were searchedProspective randomised controlled trials (RCTs), clinical controlled trials (CCTs) and observational studies of Class I and/or Class II resin composite restorations with a sample size of more ...