aPICOC analysis has been widely used in informing development of good research questions and will be adopted for this research. In highlighting the importance of PICO Analysis, Willson (2007) observes that this analysis plays an important role in research in as far as formulation of appropriate re...
This is because we consider defining the population (including animal populations) and outcomes as more straightforward given their relation to the existing PICO literature. We attempted to support our framework by examples. Table 1. Five paradigmatic approaches and examples for identifying the exposure...
Not necessarily something I want to bet the farm on, but it is possible. Our current bureaucratic overlords may have microshreds of conscience, but as a practical matter, once one drops below “shred”, even three-order-of-magnitude measurement (mini, micro, nano, pico) is not terribly r...
It is our concern that European Union Directive 2010/63/EU with its current project evaluation of animal research in the form of a harm–benefit analysis may lead to an erosion of the credibility of research. The HBA assesses whether the inflicted harm o