Versions Notes Abstract The Golgi apparatus is a membrane organelle located in the center of the protein processing and trafficking pathway. It consists of sub-compartments with distinct biochemical compositions and functions. Main functions of the Golgi, including membrane trafficking, protein glycosylation...
Golgi body is an organelle that is bound by a membrane in eukaryotic cells. It is also called Golgi apparatus or Golgi complex. The Golgi body is situated in the cytoplasm.
Next, we tried to identify the transcription factor responsible forSIRT2upregulation under Golgi stress. The Golgi apparatus is hypothesized to integrate and transduce stress stimuli to the nucleus14. One of the mechanisms is through the CREB3 transcription factor25. Thus, we decided to test if C...
Targeted Chlamydia mutant strains allow us to link the DUB activity of ChlaDUB1 and the related, dedicated DUB ChlaDUB2 to fragmentation of the host Golgi apparatus, a key process in Chlamydia infection for which effectors have remained elusive. Our work illustrates the incredible versatility of ...
[60,61] but this concept has recently been challenged. It was shown that mutants of the ER-resident p24 protein family that lack the di-lysine ER retrieval signal in their cytosolic domain and thus escape their first instance of sorting at the Golgi apparatus are indeed transported to the ...
[60,61] but this concept has recently been challenged. It was shown that mutants of the ER-resident p24 protein family that lack the di-lysine ER retrieval signal in their cytosolic domain and thus escape their first instance of sorting at the Golgi apparatus are indeed transported to the ...
However, these probes are not very specific as they can be taken up by almost all sub-organelles and exhibit Pearson coefficients of 0.60 ± 0.05 and 0.426 in the Golgi apparatus. Hence, there is still a strong need for the development of an efficient probe that is highly specific for a ...
Overall, this review aims to provide insights into the multifunctional nature of the Golgi apparatus and its impact on innate immunity. Keywords: immunology; innate immunity; Golgi-apparatus; intracellular-signaling; NLRP3-inflammasome1. Introduction Camillo Golgi’s 1898 discovery of the Golgi ...