Separate roles for the Golgi apparatus and lysosomes in the sequestration of drugs in the multidrug-resistant human leukemic cell line HL-60. J Biol Chem. 2003; 278:50234-50239.Gong Y, Duvvuri M and Krise JP: Separate roles for the Golgi apparatus and lysosomes in the sequestration of ...
Novikoff PM, Novikoff AB, Quintana N et al. Golgi apparatus, GERL, and lysosomes of neurons in rat dorsal root ganglia, studied by thick section and thin section cytochemistry. J Cell Biol 1971; 50(3):859–86. ArticleCASPubMedGoogle Scholar Goldfischer S, Essner E, Novikoff AB. The loca...
in H & E-stained sections of thecellssynthesizing and secretingprotein, the Golgi apparatus is well-developed and its site could be seen as a negative Golgi image, a clear pale area near the nucleus against the basophilic cytoplasm e.g. inplasma cells. It can be seen in histological s...
- Golgi Apparatus- Mitochondria- Lysosomes- Ribosomes Step 2: Classify Organelles by Membrane PresenceNext, we classify these organelles based on whether they have membranes or not:- Membrane-bound Organelles: - Nucleus (double membrane) - Endoplasmic Reticulum (single membrane) - Golgi Apparatus (...
Related to Golgi apparatus:endoplasmic reticulum,nucleus,Lysosomes,Plastids n. A network of stacked membranous vesicles, present in most living cells, that stores and modifies proteins and other macromolecules and transports them within the cell or excretes them from the cell. Also calledGolgi body,...
The Golgi apparatus (GA) is a key organelle in biosynthetic membrane transport. It is a morphologically complex compartment composed of a central domain of stacked flattened cisternae, flanked at its entry and exit sites by tubular networks with sorting functions, thecis- andtrans-Golgi networks (...
To examine effect of the Swedish mutation on intracellular APP trafficking, we transiently transfected SN56 cells with βAPPsw-paGFP along with plasmids expressing compartment markers for the Golgi apparatus and lysosomes. The same pulse-chase paradigm was performed on these cells, targeting the GalT...
These vesicle form cell structures calledlysosomes. Molecules dispatched from the Golgi may also be reprocessed by the Golgi. Golgi Apparatus Assembly The Golgi complex is composed of flat sacs known as cisternae. The sacs are stacked in a bent, semicircular shape.Image credit: Louisa Howard ...
Using both live LysoTracker DND-26 imaging and Golgi antibodies, we found that the Golgi apparatus is cast off from the acrosomal vesicle and migrates toward the sperm tail in elongated spermatids. The Golgi is discarded in the cytoplasmic droplet and is undetectable in mature ejaculated ...
Using APP-paGFP, we show that APP is rapidly trafficked from the Golgi apparatus to the lysosome; where it is rapidly cleared. Chloroquine and the highly selective γ-secretase inhibitor, L685, 458, cause the accumulation of APP in lysosomes implying that APP is being cleaved by secretases ...