20 Both trial data and real-world data analyses have shown that the survival outcomes of older adults are similar to younger patients with CAR T-cell therapy with higher rates of cytokine release syndrome and neurotoxicity being offset by higher response rates; hence, all older adults eligible fo...
Additionally, inborn errors of OAS-RNase L have been found to be associated with multisystem inflammatory syndrome in children (MIS-C), which involves the release of an excessive amount of inflammatory cytokines upon SARS-CoV-2 infection [58, 59]; this downstream effect highlights the importance...