The research group of Patil and Gandon recently documented the gold-catalyzed Heck reaction, demonstrating the utilization of simple aliphatic alkenes as substrates. This approach does not need electronically biased olefins and offers a distinct regioselectivity when compared to the Heck reaction catalyzed...
T. Gold-catalyzed heck reaction. J. Am. Chem. Soc. 145, 8810–8816 (2023). 49. Wang, W., Xu, B. & Hammond, G. B. Efficient synthesis of gamma- keto esters through neighboring carbonyl group-assisted regiose- lective hydration of 3-alkynoates. J. Org. Chem. 74, 1640–1643 (...
The enclosed methodology leverages a Mizoroki–Heck-type reaction to generate a neopentylpalladium species. This species can undergo... AD Marchese,AG Durant,M Lautens 被引量: 0发表: 2021年 Synthesis of Chiral Trispirocyclic Oxindoles via Organic-Base/Au(I)-Catalyzed Sequential Reactions Chiral ...
The gold clusters can be formed in situ or generated ex situ and introduced into the reaction media. Salts, complexes, and nanoparticles (NPs) can be used as a starting source of gold. Ts=para-toluenesulfonyl.关键词: carbon–carbon bond formation carbon–heteroatom bond formation gold ...
we developed a method for the synthesis of substituted pyrroles via gold-catalyzed addition–cyclization cascade (Scheme 1).24,25 This reaction proceeds via gold-mediated auto-tandem catalysis,26 where the initially generated gold acetylide 527 adds to oxonium ion 6 to give intermediate 7, which ...
An unexpected domino Heck/alkylation reaction observed during the synthesis of FR900482 was investigated and explored. Finally, synthetic studies were undertaken toward NK154183A, a member of the dunaimycin family of natural products whose efficient synthesis may be envisioned based on our previous ...
Heck reactionTetradentate ligandAllenesChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a Full Text option. The original ...
Room-Temperature, Ligand- and Base-Free Heck Reactions of Aryl Diazonium Salts at Low Palladium Loading: Sustainable Preparation of Substituted Stilbene De... The Pd(OAc)2-catalyzed Heck reaction of aryl diazonium salts with 2-arylacrylates led to cis-stilbenes with good to excellent stereoselect...
Optimization of the reaction conditions However, to the best of our knowledge, simultaneous construction of multiple chiralities by asymmetric gold catalysis has not been reported so far, this hypothesis faced considerable challenges: (1) the universal and efficient asymmetric intramolecular desymmetric cy...