Research has shown the safety and efficacy of keeping LDL at very low levels for CVD prevention. Therefore, experts recommend intense LDL-lowering approaches starting at young ages, promoting the mantras "the lower, the better" and "the earlier, the better." This commentary discusses the ...
of cardiovascular events.14 Based on these data and the concern for patients not meet- ing goal LDL-C, it seems prudent to be more aggressive with initial statin dosing and select the initial starting statin dose based on the degree of LDL-C lowering required in each indi- vidual patient....
Statistical methods were used to screen for possible predictors of dyslipidemia. Results Patients with ACI or OCI had higher total cholesterol (TC) and LDL-C levels than did the control group (all P < 0.05). According to European (94.7%, 89.0% and 13.4%, P < 0.01), American (...
Patients were categorized into early or non-early target LDL-C groups based on LDL-C measured 4–12 weeks post-discharge (<55 vs. ≥55 mg/dl). The primary outcome was recurrent MACEs, including myocardial infarction, ischemic stroke, all-cause mortality, hospitalization for unstable angina, ...
(EAS)4 and the French National Authority for Health (Haute Autorité de Santé [HAS]).5, 6 As of 2006–2007,7 the vast majority of high-risk patients, according to the definition by either guideline, had not achieved the recommended LDL-C goals, largely due to insufficient treatment ...
Impact of HDL-cholesterol in patients achieved LDL cholesterol management goal for primary prevention of coronary artery disease: Comparison between the lipid profiles and coronary CT angiographyN., YokoyamaK., KonnoT., SaitoR., IinoT., Teramoto...
Based on patient CV risk, the guidelines identified LDL as the primary target for cholesterol- lowering therapy. The guidelines also recommended the use of statins for both primary and secondary prevention based on patient risk profile. With strong evidence of effectiveness of statins in secondary ...
which established increasingly stringent goals for the lowering of LDLlevels in primary and secondary coronary prevention.[14,15] Among other guideline changes, th Adult Treatment Panel (ATP) III[15] extended the LDL-C goal of < 100 mg/dL (prev...
Lipid management and LDL-C goal attainment in primary prevention: An analysis of EPHESUS studydoi:10.1016/j.atherosclerosis.2020.10.518O. BasaranV. DoganG.O. MertK.U. MertM. KaykciogluAtherosclerosis
LDLElevated low density lipoprotein cholesterol (LDL) has been identiied as one of the strongest correctable risk factors for cardiovascular disease in patients with diabetes. The reduction in cardiovascular events with pharmacological therapy aimed at LDL lowering is well documented in both primary ...