Once GnRH is released from the hypothalamus, it travels to the pituitary gland. There, it binds toGnRH receptors on the surface of gonadotrope cells, which make and release the gonadotropins: LH and FSH [4]. GnRH and its receptors can also be found outside the hypothalamus and pituitary....
Ghrelin is a newly discovered peptide that is released from the stomach and from neurons in the hypothalamic arcuate nucleus (ARC) and potently stimulates ... Daisuke,Kohno,Hong-Zhi,... - 《Diabetes》 被引量: 415发表: 2003年 Interleukin-1 Directly Stimulates the Release of Corticotrophin Rele...
GnRHR promoter activity is also stimulated by the neuropeptide, pituitary adenylate cyclase activating polypeptide (PACAP). Hypothalamic PACAP is released into the portal vasculature, binding to specific PACAP receptors on gonadotrope cell membranes and acting to augment gonadotropin secret...
When perifused in Ca(2+)-free medium, pituitary glands from juveniles of both sexes and from adult cockerels but not those from laying hens, released LH in response to cGnRH-I. This release occurred at the same time as the spike phase of the response seen in the presence of extracellular...
Here GnRH is released into the pituitary portal blood vessels for delivery to the anterior pituitary to elicit the secretion of luteinizing hormone (LH) and follicle- stimulating hormone (FSH)1. Alterations in the development of this system or in the secretion of GnRH are associated with a ...
GnRH is a key neurohormone responsible for the central regulation of gonadotropin (LH, FSH) secretory function. It is released from the nerve terminals into the hypophysial-portal circulation in a pulsatile manner and, at pituitary level, it interacts with high-affinity, G protein-coupled recepto...
When perifused in CA2+-free medium, pituitary glands from juveniles of both sexes and from adult cockerels but not those from laying hens, released LH in response to cGnRH-I. This release occurred at the same time as the spike phase of the response seen in the presence of extracellular ...
Gonadotropin-releasing hormone (GnRH), the first key hormone of reproduction, is synthesized in the hypothalamus and is released in a pulsatile manner to s... HS Shacham - 《Frontiers in Neuroendocrinology》 被引量: 232发表: 1998年 Signal transduction of the gonadotropin releasing hormone (GnRH)...
GnRH is released into the portal vascular system in a pulsatile pattern. While GAP inhibits prolactin secretion in rats, its physiological function in other mammals remains unknown. GnRH initiates neuroendocrine processes that regulate gametogenesis, gonadal steroid production, and pituitary hormone release...
To study the concentrations and activity of the hormones released from the cells, the following points should be addressed: (i) whether these hormones are secreted in a constitutive or regulated way; (ii) what ratio of the induced endogenous hormone can be secreted; (iii) the results of ...