Selection criteria for initiation and renewal of luteinizing hormone-releasing hormone agonist therapy in patients with prostate cancer: a French prospective observational study[J/OL]. Ther Adv Urol, 2014, 6(6): 205-214. ...
During COS for IVF, GnRH analogs (Table 1), including a GnRH agonist and antagonist, are applied to inhibit the premature LH surge to prevent spontaneous ovulation and subsequent loss of oocytes (Kiesel et al., 2002). Despite their efficient prevention of the premature LH surge,GnRH agonistsan...
The role of GnRH agonist cotreatment in addition to cryopreservation of embrya, oocytes, or ovaries[J]. The oncologist, 2007, 12(9): 1044-1054. [5] McArdle C A, Franklin J, Green L, et al. Signalling, cycling and desensitisation of gonadotrophin-releasing hormone receptors[J]. The Jour...
More specifically, combination of drugs characterized in that the GnRH agonist is combined with a chemical selected from among SERM, SARM, sex hormone synthesis inhibitors, receptor-type tyrosine kinase inhibitors, bone metabolism regulators, drugs for immunotherapy, cytokine/chemokine inhibitors and ...
对于绝经前女性乳腺癌和前列腺癌患者,促性腺激素释放激素类似物(GnRHa)是重要的治疗手段,其作用机制是模拟GnRH的生理作用,竞争性抑制垂体分泌促性腺激素,导致卵巢分泌的性激素减少,从而达到治疗肿瘤的目的。目前临床上常用的GnRHa包括植入剂...
Prescribing a GnRH agonist is an example of androgen deprivation therapy, also known as ADT.Examples of GnRH agonists available today in the USA are: GnRH agonists are approved and used in the USA for palliative treatment in patients with advanced prostate cancer. The benefits of this type of ...
3. Antoniazzi F, Zamboni G Central precocious puberty: current treatment options. Paediatr Drugs 2004:6:211-231. 4. 郭红宇, 高云荷 GnRH类似物的研究进展. 中国实用妇科与产科杂志 2005:21:3. 5. Kaplowitz PB, Oberfield SE Reexamination of the age limit for defining when puberty is precocious...
The selection of developmentally competent human gametes may increase the efficiency of assisted reproduction. Spermatozoa and oocytes are usually assessed according to morphological criteria. Oocyte morphology can be affected by the age, genetic charact
[6] Agarwal P, Rupenthal ID. Injectable implants for the sustained release of protein and peptide drugs. Drug Discov Today. 2013 Apr;18(7-8):337-49. doi: 10.1016/j.drudis.2013.01.013. [7] Dean RL. The preclinical development of Medisorb Naltrexone, a once a month long acting injectio...
The selection of developmentally competent human gametes may increase the efficiency of assisted reproduction. Spermatozoa and oocytes are usually assessed according to morphological criteria. Oocyte morphology can be affected by the age, genetic charact