Protective Effect of Neutrophils on Cartilage ECM Degradation by GMOCS-Exos. Note(A) Co-culture model of GMOCS-Exos/neutrophils/damaged chondrocytes; (B) mRNA levels of COL2, SOX9, and MMP13 detected by RT-qPCR; (C) Protein expression levels of COL2, SOX9, and MMP13 detected by Western...
Choi YA, Lim J, Kim KM, Acharya B, Cho JY, Bae YC, Shin HI, Kim SY, Park EK: Secretome analysis of human BMSCs and identification of SMOC1 as an important ECM protein in osteoblast differentiation. J Proteome Res. 2010, 9: 2946-2956. CAS PubMed Google Scholar Zhang H, Lu W,...
ECM modulation, and activation of the Notch and hedgehog neurodevelopmental pathways. This multifaceted mechanism of action is unique among existing ALS drug candidates and may be applicable to multiple neurodegenerative