Alignments of the protein sequence of the dimeric thermophilic glycyl-tRNA synthetase (Gly-tRNA synthetase) derived from its gene with sequences of other dimeric Gly-tRNA synthetases revealed an atypical character of motif 1 in all these class 2 synthetases. Interestingly, the sequence of the ...
glycyl-tRNA-aminoacylation网络氨酰化网络释义 1. 氨酰化 甘氨酰tRNA 氨酰化 (glycyl-tRNA aminoacylation) 3: gars pars2 polg2谷氨酸脱羧琥珀酸 (glutamate decarboxylation to succinat…www.eiaab.cn|基于1 个网页© 2025 Microsoft 隐私声明和 Cookie 法律声明 广告 帮助 反馈...
Mutations in tyrosyl-tRNA synthetase, glycyl-tRNA synthetase and alanyl-tRNA synthetase from patients and mice models were identified to cause two subtypes of Charcot-Marie-Tooth disease and cerebellar Purkinje cell loss, respectively. 近期在对一些患有神经退行性疾病的病人和小鼠模型的研究中发现,位于酪...
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Neddylation is a post-translational modification that controls cell cycle and proliferation by conjugating the ubiquitin-like protein NEDD8 to specific targets. Here we report that glycyl-tRNA synthetase (GlyRS), an essential enzyme for protein synthesis
Here we report that glycyl-tRNA synthetase (GlyRS), an essential enzyme for protein synthesis, also plays a critical role in neddylation. In human cells, knockdown of GlyRS, but not a different tRNA synthetase, decreases the global level of neddylation and causes cell cycle abnormality. This ...
Neddylation is a post-translational modification that controls the cell cycle and proliferation by conjugating the ubiquitin-like protein NEDD8 to specific targets. Here we report that glycyl-tRNA synthetase (GlyRS), an essential enzyme in protein synthesis, also plays a critical role in neddylation...
Glycyl-tRNA Synthetase as a Potential Universal Regulator of Translation Initiation at IRES-IGlycyl-tRNA Synthetase as a Potential Universal Regulator of Translation Initiation at IRES-INikonovaE.Y.MihaylinaA.O.NemchinovaM.S.GarberingentaconnectMolecular Biology C/c of Molekuliarnaia Biologiia...
Abnormal Codon Recognition of Glycyl-tRNA from the Posterior Silk Glands of Bombyx mori Two species of glycine tRNA (tRNA1Gly and tRNA2Gly were purified from the posterior silk glands of Bombyx mori. Digestion of tRNA1Gly with RNase Tl reveale... M Kawakami,PA Tsonis,K Nishio,... - 《...
Here we report a pathway that features glycyl-tRNA instead. During the biosynthesis of pyrroloiminoquinone-type natural products such as ammosamides, peptide-aminoacyl tRNA ligases append amino acids to the C-terminus of a ribosomally synthesized peptide. First, AmmBCTrp adds Trp in a Trp-tRNA-...