cellsGenetic defects in like-glycosyltransferase (LARGE) cause congenital muscular dystrophy with central nervous system manifestations. The underlying molecular pathomechanism is the hypoglycosylation of α-dystroglycan (α-DG), which is evidenced by diminished immunoreactivity to IIH6C4 and VIA4-1, ...
Exostosin-like 2 regulates FGF2 signaling by controlling the endocytosis of FGF2 Biochim. Biophys. Acta Gen. Subj., 1862 (2018), pp. 791-799 View PDFView articleView in ScopusGoogle Scholar 23 D.E. Anderson, J. Cui, Q. Ye, B. Huang, X. Tan Orthogonal genome-wide screenings in bat...
They exhibit a wide variety of beneficial biological activities, such as anti-oxidant1, anti-inflammatory2, anti-cancer3 and anti-diabetic activities4. Phloretin, a precursor of phloridzin, exhibits addi- tional pharmacologically biological functions like anti-tumor5 and anti-estrogen activities6, ...
We aimed to investigate the potential prognostic value and oncogenic role of GLT8D1/2 in GC.#The relationship between GLT8D1/2 and GC was evaluated through comprehensive bioinformatics approaches. A series of factors like gene expression patterns, Kaplan-Meier survival analyses, Cox regression ...
Neither a TATA- nor a TTGA-like sequence was observed within the cloned DNA fragment. However, the fragment was expressed in Escherichia coli by the lac promoter of pUC19 and 74% of the total activity was secreted into the fermentation medium. The amino acid sequence of the mature CGTase ...