Glycosylation site prediction using ensembles of Support Vector Machine classifiers. BMC bioinformatics. 2007; 8 :438. doi: 10.1186/1471-2105-8-438. [ Cross Ref ]Caragea C, Sinapov J, Silvescu A, Dobbs D, Honavar V (2007) Glycosylation site prediction using ensembles of Support Vector ...
Glycosidic linkage—the site of glycan (oligosaccharide) binding Glycan composition—the types of sugars that are linked to a particular protein Glycan structure—branched or unbranched chains Glycan length—short- or long-chain oligosaccharides
From a machine learning point of view, the problem of glycosylation site prediction can be formulated as a binary classification problem: Given a protein sequenceSof lengthN,S=s1s2⋯sNover the alphabet Σ of amino acids, |Σ| = 20,si∈Σ,i= 1,⋯,NandS∈Σ*, the task is to predict...
Using an optimized method protocol, we determined the glycosylation site occupancy from four proteins of hepatic and lymphatic origin from CDG and NAFLD patients. We found variable degrees of site occupancy, depending on the tissue of origin and the disease condition. In CDG glycosylation sites of ...
必应词典为您提供N-glycosylation-site的释义,网络释义: 醣化点;具有兩个醣化点;
Contemporary influenza A H3N2 viruses circulating since 2016 have acquired a glycosylation site in the neuraminidase in close proximity to the enzymatic active site. Here, we investigate if this S245N glycosylation site, as a result of antigenic evolution, can impact binding and function of human ...
intracellular pools, and impact glycoform distributions, but with varied results. These variations can be attributed to five key factors: Differences between cell platforms (enzyme/transporter expression levels); differences betweenrecombinant proteinsproduced (glycan-site accessibility); the fermentation and ...
First, former N-glycopeptides were identified as peptides containing one or more N-glycosylation site(s), either N-X!-S, N-X!-T, N-X!-V or N-X!-C, where the asparagine residue at position 1 in the N-glycosylation sequon is deamidated, and X! represents any amino acid apart ...
Glycosylation analysis studies of proteins, including assessment of glycosylation site, carbohydrate content and glycan structure in line with ICH guidelines Glycosylation is a common post translational modification (PTM) and involves enzymatic addition of a carbohydrate (or glycan) to certain sites within...
网络释义 1. 潜在糖基化位点 慢性乙型肝炎急性发作与血清HBV DNA含量关系... ... 病毒 Viruses潜在糖基化位点Potential glycosylation site合计 Total ... www.qnr.cn|基于10个网页 2. 可能的糖基化位点 分子生物学与生物工程词... ...potential glycosylation site潜在糖基化位点,可能的糖基化位点potential ...