Glycoproteins are complex macromolecules composed of a polypeptide backbone to which one or more carbohydrate units are attached. Based on the linkage between the peptide and sugar, one can classify several types of glycoproteins (Spiro, 1970). The linkage betweenN-acetylglucosamine and asparagine throu...
These glycoproteins are composed of repeating units of the triglycopeptide, Ala-Ala-Thr-O-disaccharide. The disaccharide is galactosyl-N-acetylgalactosamine, with internal linkage β, 1→3 (ref. 6) or (β, 1→4 (ref. 7). Three active glyco-proteins differing only in polymer length have ...
Pancreatic cystic neoplasms (PCNs) are recognized as precursor lesions of pancreatic cancer, with a marked increase in prevalence. Early detection of malignant PCNs is crucial for improving prognosis; however, current diagnostic methods are insufficient for accurately identifying malignant PCNs. Here, we...
Protein stains of these gels showed that this membrane is composed of po... David,R.,Phillips - 《Biochemistry》 被引量: 319发表: 1972年 Reliability of molecular weight determination of proteins by polyacrylamide gradient gel electrophoresis in the presence of sodium dodecyl sulfate. Thirty-four ...
The envelope glycoproteins of human immunodeficiency virus type 1 (HIV-1) function as a trimer composed of three gp120 exterior glycoproteins and three gp41 transmembrane proteins. Soluble gp140 glycoproteins composed of the uncleaved ectodomains of gp120 and gp41 form unstable, heterogeneous oligomers...
Crimean-Congo hemorrhagic fever virus (CCHFV) is a biosafety level-4 pathogen requiring urgent research and development efforts. The glycoproteins of CCHFV, Gn and Gc, are considered to play multiple roles in the viral life cycle by interactions with hos
Pili, composed of monomeric pilin subun... R Ramphal,L Koo,KS Ishimoto,... - 《Infection & Immunity》 被引量: 325发表: 1991年 Identification of a Moraxella catarrhalis outer membrane protein exhibiting both adhesin and lipolytic activities. The UspA1 and Hag proteins have previously been ...
In the rat small intestine, galactosyltransferases are the enzymes implicated in the biosynthesis of glycoproteins of the brush-border membranes and mucins... LMC Biol - 《Metabolism-clinical & Experimental》 被引量: 18发表: 2000年 Extracellular Structural and Secretory Proteins The extracellular matri...
The gp120 core is composed of inner and outer domains, which reflects the likely orientation of gp120 in the assembled trimer, and a bridging sheet. Components of both domains and the bridging sheet contribute to CD4 binding. CD4 binds in a recessed pocket on gp120 to a surface that is ...
aThe virus particle is composed of at least 34 proteins, many of which are post-translationally modified by cellular and viral enzymes. The lipid envelope contains at least 11 virus-encoded glycoproteins that participate in many aspects of the virus life cycle including attachment and entry,cell-to...