Define glycolytic. glycolytic synonyms, glycolytic pronunciation, glycolytic translation, English dictionary definition of glycolytic. n. A metabolic process that occurs in nearly all living cells in which glucose is converted in a series of steps to pyr
Increasing amounts of NADH and/or ATP act as negative allosteric effectors controlling the flux through glycolysis [1,2]. Furthermore, metabolites of the CAC are able to regulate glycolysis. Higher rates of fatty acid oxidation lead to accumulation of citric acid, the first intermediate of CAC....
tuber-specific overexpression of PGM has resulted in unaltered yield despite enhancedTCA cycleflux, but with reduced glycolysis (Table 2, Section 1)[8, 24, 25]. These studies concluded that perhaps activity of cytosolic PGM is optimal for glycolysis and starch synthesis[24]. However, constitutive...
Glucose metabolism;Glycolysis;Glycolytic inhibitors;Tumor metabolism;Warburg effect Definition The strict dependence of cancer cells on glycolysis for ATP synthesis stimulates the development of molecules acting as inhibitors of enzymes distributed along the glycolytic or the pentose phosphate pathway. Several ...
(b) Flux-concentration curves of normalized PFK flux and the allosteric activator FBP, with σ = 0.25. The two different curves correspond to the two different estimates of X0.5. The most frequent way of describing PFK kinetics has been to use some kind of Monod-Wyman-Changeux (MWC) rate...