CAF also has strong glycolysis ability and releases a large amount of lactate outside the cell. After that, this part of lactate will be absorbed by the cancer cells, converted into pyruvate in the cancer cell
CAF also has strong glycolysis ability and releases a large amount of lactate outside the cell. After that, this part of lactate will be absorbed by the cancer cells, converted into pyruvate in the cancer cell plasma, and then provide continuous energy for the proliferation of cancer cells ...
(Fig. 151.2), present in the innermitochondrial membrane, is the principal source of energy in muscle and other tissues. The flow of electrons from the reduced form of nicotineadeninedinucleotide(NADH) to the lastenzymein theelectron transport chain, cytochrome-coxidase (complex IV), releases ...
Hypoxic microenvironment deregulates metabolic homeostasis in cancer cells albeit the underlying mechanisms involved in this process remain hitherto enigmatic. 14-3-3ζ/Yes-associated protein (YAP) axis plays a principal role in malignant transformation
This hypothesis postulates that glutamate, released upon neural stimulation and taken up by astrocytes, activates glycolysis, which produces and releases L-lactate that is utilized aerobically by neurons. Pellerin and Magistretti described this L-lactate production by astrocytes as ‘aerobic glycolysis’,...
This hypothesis postulates that glutamate, released upon neural stimulation and taken up by astrocytes, activates glycolysis, which produces and releases L-lactate that is utilized aerobically by neurons. Pellerin and Magistretti described this L-lactate production by astrocytes as 'aerobic glycolysis', ...
This hypothesis postulates that glutamate, released upon neural stimulation and taken up by astrocytes, activates glycolysis, which produces and releases L-lactate that is utilized aerobically by neurons. Pellerin and Magistretti described this L-lactate production by astrocytes as ‘aerobic glycolysis’,...