In tumor cells, fermentation from glucose to lactate occurs more frequently thanoxidative phosphorylation, even in the presence of sufficient oxygen. This phenomenon is calledaerobic glycolysisor theWarburg effectand was raised by Otto Warburg in the 1920s. The meaning of this effect in tumor cells...
Therefore, it is of great meaning to explore effective molecular targets for GBM treatment. G protein family is considered to be a vital regulator in cancer progression, which can serve as potential targets for cancer treatment6,7. G protein subunit Gamma 5 (GNG5) is a member of the G ...
SARS-CoV-2 infection causes COVID-19, a severe acute respiratory disease associated with cardiovascular complications including long-term outcomes. The presence of virus in cardiac tissue of patients with COVID-19 suggests this is a direct, rather than secondary, effect of infection. Here, by exp...
The control of gluconeogenesis in animals has been the subject of extensive reviews, which provide additonal information and references to early work. Considering, however, the progress made during the last two the three years, it seems appropriate to reconsider the physioloical meaning of the ...