Regulation of glycogen phosphorylase a phosphatase in Neurospora crassa. Biochim Biophys Acta. 1973 Feb 28; 297 (2):399–412.T611ez de Ifion M. T., Torres H. N. (1973) Regulation of glycogen phosphorylase a phosphatase in Neurospora crassa. Biochim. Biophys. Acta 297, 399-417....
Glycogen phosphorylase (GP) isoenzymes GPbb and GPmm impose distinctive control of ventromedial hypothalamic nucleus (VMN) glucose-regulatory neurotransmission during hypoglycemia, but lactate and/or gliotransmitter involvement in those actions is unknown. Lactate or the octadecaneuropeptide receptor ...
We discovered glycogen phosphorylase (GP) as a novel substrate of malin. GP is vital in catabolism of cellular glycogen. The expression of GP was decreased in liver and skeletal muscle tissues from malin knockout mice. Our data suggest that malin does not target GP for proteasomal degradation....
Ex- pression and regulation of glycogen phosphorylase in preneo- plastic and neoplastic hepatic lesions in rats. Virchows Arch B Cell Pathol Incl Mol Pathol 1987;53:44-51. 164 Ehemann V, Mayer D, Hacker HJ, Bannasch P. Loss of ade- nylate cyclase activity in preneoplastic and neoplastic...
Structure-based amino acid alignment shows conservation of the residues and domains involved in catalysis and allosteric regulation by glucose 6-phosphate but high divergence at domains involved in phosphorylation-dependent regulation and AMP binding in fungi and animals. Protist phosphorylases, as their ...
The vast majority of glucose that is released from glycogen comes fromglucose-1-phosphate, which is formed when theenzymeglycogen phosphorylase catalyzes the breakdown of the glycogenpolymer. In the liver,kidneys, andintestines, glucose-1-phosphate is converted (reversibly) toglucose-6-phosphateby the...
et al. Regulation of glycogen synthase and phosphorylase during recovery from high-intensity exercise in the rat. Biochem. J. 322, 303–308 (1997). Article PubMed PubMed Central MATH Google Scholar Blackwood, S. J., Hanya, E. & Katz, A. Effect of postexercise temperature elevation on ...
Regulation is based on the phosphorylation and dephosphorylation of the key regulatory enzymes, which include: Glycogen synthase (glycogenesis): active when dephosphorylated Glycogen phosphorylase (glycogenolysis): active when phosphorylated Glycogen phosphorylase kinase: The conversion of inactive glycogen...
Name the second messenger for glucagon and explain how it exerts its regulation of glycogen synthesis and glycogen phosphorolysis. Are these two processes up- or down-regulated? Glycogen phosphorylase: a.) releases glucose-1-phosphate from glycogen b.) is activated by AMP c.) exists in tw...
of catalytic subunit is 35,000; major enzyme in regulation of glycogen metabolism in skeletal muscle; dephosphorylates glycogen phosphorylase, β-subunit of phosphorylase kinase, and at least three sites of glycogen synthase; regulated by inhibitor-1, inhibitor-2, and GSK-3 + Mg2+. ATP). 2 ...