Glycine betaine (GB) is a natural vitamin that has the potential to lower blood pressure. This work attempted to investigate the precise mechanism of action of GB in spontaneous hypertension.#Spontaneous hypertension rats (SHRs) were administrated with 100, 200 or 400mg/kg of GB by gavage, ...
Robb:Yeah, so the DELISH study is super interesting, recently released. We have links to that in the show notes. The Diabetes Education to Lower Insulin Sugars in Hunger, the DELISH study, a really well done study. They weren’t trying to be mega ketogenic. The main advice that they mad...
Objectives: This study aimed to investigate whether lower plasma Gly concentrations in older adults are independently associated with (visceral) adiposity, age, sex, presence of chronic disease, and glucose intolerance, and whether they are caused by a reduced Gly whole-body production (WBP) and/...
Our findings suggest that the inverse genetic association of glycine with blood pressure may at least partly explain the genetic glycine-CHD association. High blood pressure is a major risk factor for cardiovascular diseases29and glycine supplementation has been shown to lower blood pressure in rodents...
Figure 2. Targets of neurotoxic agents acting on PNS cholinergic nerve fibers (upper portion), terminals (lower midportion), and neuromuscular synapses (lowest portion). ACh, acetylcholine; AChase, acetylcholinesterase; and CAT, choline acetyltransferase. Acetylcholine receptors provide another target for...
Dietary taurine seems to show positive effects on cardiovascular diseases through several mechanisms [34], to lower blood pressure in ...Sugiyama K, Kanamori H, Tanaka S. Correlation of the plasma cholesterol-lowering effect of dietary glycine with the alteration of hepatic phospolipid composition ...
Menopause symptoms can affect sexuality. Along with menopause, women experience lower levels of the hormone estrogen. One of the effects of lowered estrogen levels is a decrease in blood supply to the vagina, which causes vaginal dryness. This can result in painful or uncomfortable intercourse. Wat...
As a biomolecule becomes more and more complicated and large (amino acid–peptide–protein), the frequency exponent 1-α of the Cole–Cole equation becomes higher (α lower), indicating a broader distribution of time constants. Sign in to download full-size image Figure 4.4. Cole–Cole plots ...
Muscle, total red blood cell, and reduced red blood cell glutathione levels increased by 165%, 225%, and 259%, respectively. Oxidative stress levels decreased — TBARS and F-2 isoprostanes were 72% lower. Gait speed, upper-extremity (grip strength), and lower-extremity (chair-stand test) ...
involving N-methyl-D- aspartate (NMDA) receptors in the dorsal vagal complex (DVC) to suppress glucose production18, while these same DVC NMDA receptors are required for intestinal sensing of nutrients, as well as metformin and resveratrol, to lower glucose production and food intake5,19–22. ...