8kb),相邻的一个开读框(ORF)与甘氨酸/D-型氨基酸氧化酶基因相似。 Adjacent to dadX one ORF similar to a putative glycine/D-amino acid oxidase gene have been found.
d-amino acidGlycine oxidase (GO) is an enzyme that catalyzes the oxidation of the primary and secondary amines of various chemicals, including glycine, and the enzyme has been applied in a variety of fields, such as biosensor and genetically modified glyphosate resistance plants. Here, we report...
In the third pathway of glycine degradation, glycine is converted to glyoxylate by D-amino acid oxidase. Glyoxylate is then oxidized by hepatic lactate dehydrogenase to oxalate in an NAD+-dependent reaction. The half-life of glycine and its elimination from the body varies significantly based on ...
Proparglyglycine (2-amino-4-pentynoate) and vinylglycine (2-amino-3-butenoate) have been examined as substrates and possible inactivators of two flavo enzymes, D-amino acid oxidase from pig kidney and L-amino acid oxidase from Crotalus adamanteus venom. Vinylglycine is rapidly oxidized by bo...
AutophagyMAOMonoamine Oxidase $46 In Stock Size QTY Cited Taurine 2-Aminoethanesulfonic acid T0022107-35-7 Taurine (2-Aminoethanesulfonic acid) is an organic acid widely distributed in animal tissues and is one of the constituents of bile acids. Taurine is involved in a number of processes re...
Vinylglycine and propargylglycine: complementary suicide substrates for L-amino acid oxidase and D-amino acid oxidase 喜欢 0 阅读量: 14 作者:Patrick,Marcotte,Christopher,Walsh DOI: 10.1021/bi00659a021 被引量: 102 年份: 1976 收藏 引用 批量引用 报错 分享 全部来源 求助全文 dx.doi.org ...
Glycine and D-serine are endogenous ligands to the NMDA modulatory site62, and ligands modulating NMDA receptor transmission, have being developed such as GlyT-1 inhibitors to potentially elevate brain glycine or targeting enzymes, such as d-amino acid oxidase (DAAO) to slow the breakdown and ...
Glycine is also oxidized by D-amino acid oxidase, an FAD protein: NH3+−CH2glycineCOO−+O2+H2O→ CHOCOO−glyoxalate+NH4++H2O2 Glyoxalate can be transaminated to glycine, reduced to glycolate, converted to α-hydroxy-β-ketoadipate by reacti...
Glycine oxidase from Bacillus subtilis is a homotetrameric flavoprotein of great potential biotechnological use because it catalyzes the oxidative deamination of various amines and D-isomer of amino acids to yield the corresponding α-keto acids, ammonia/amine, and hydrogen peroxide. Glyphosate (N-phos...
Patai, S. The Chemistry of Amino, Nitroso, and Nitro Compounds and Their Derivatives Vol. 29 (Wiley, 1982). Job, V., Marcone, G. L., Pilone, M. S. & Pollegioni, L. Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein. J. Biol. Chem. 277, 6985–6993 (...