Twitter Google Share on Facebook glycine Thesaurus Medical Acronyms Encyclopedia Wikipedia gly·cine (glī′sēn′, -sĭn) n. A sweet-tasting crystalline nonessential amino acid, C2H5NO2, that is the principal amino acid occurring in sugarcane. The simplest amino acid found in protein, it is ...
Crystal structure of T-protein of the glycine cleavage system: Cofactor binding, insights into H-protein recognition, and molecular basis for understanding nonketotic hyperglycinemia. Hyung, Ho Lee,Do, Jin Kim,Hyung, Jun Ahn,Jun, Yong Ha,Se, Won Suh. Journal of Biological Chemistry . 2004...
The silence of the glycine cleavage system (GCS) encoded by gcvTHP operon reduced cas3 expression. Adding N5, N10-methylene tetrahydrofolate (N5, N10-mTHF), which is the product of GCS-catalyzed glycine, was able to activate cas3 expression. In addition, a cAMP receptor protein (CRP) ...
We have isolated the gene encoding the glycine cleavage T-protein (GCV1) of the yeast Saccharomyces cerevisiae and shown through gene disruption and enzyme assays that inactivation of GCV1 destroys glycine cleavage function. A DNA fragment encoding the GCV1 gene was cloned by PCR amplification ...
The glycine cleavage system (GCS) consists of several proteins, including glycine dehydrogenase (GLDC), GCS protein H (GCSH), aminomethyltransferase (AMT), and dihydrolipoamide dehydrogenase (DLD), which catalyze the following reversible reaction: Glycine + H4folate + NAD+ ⇄ 5,10-methylene...
Glycine cleavage system in ketotic hyperglycinemia: a reduction of H-protein activity. Pediatr. Res. 16 (1982) 5–7Hayasaka K, Narisawa K, Satoh T, Tateda H, Metoki, K, Tada K, Hiraga K, Aoki T, Kawakami T, Akamatsu H, Marsuo N. Glycine cleavage system in ketotic hyperglycin-...
PreparationFrom chloroacetic acid and ammonia; from protein sources, such as gelatin and silk fbroin; from ammonium bicarbonate and sodium cyanide; by catalytic cleavage of serine; from hydrobromic acid and methyleneaminoacetonitrile. DefinitionChEBI: Glycine is the simplest (and the only achiral) prote...
Figure 3. Some of the enzymatic activities reported for lysostaphin: (1) endopeptidase cleavage of peptidoglycan's pentaglycine bridge; (2) endo-β-N-acetylglucosaminidase cleavage of the bond between NAM and NAG; and (3) N-acetyl-muramyl-l-alanine amidase, catalyzing the cleavage of the link...
Two novel mutations in the gene encoding T-protein, a component of the glycine cleavage system, were identified in a Japanese family with nonketotic hyperglycinemia. The proband had two affected sibs, and enzymatic analysis of the liver sample from the proband revealed the T-protein deficiency....
Dong Z, Saikumar P, Weinberg JM, Venkatachalam MA (1997) Internucleosomal DNA cleavage triggered by plasma membrane damage during necrotic cell death—involvement of serine but not cysteine proteases. Am J Pathol 151(5):1205–1213 CASPubMedPubMed CentralGoogle Scholar ...