Glyceraldehyde-3-phosphate dehydrogenase(GAPDH) is a glycolytic enzyme catalyzing a reaction from glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate. The enzyme contains a cysteine residue in the catalytic site that is sensitive to oxidation and undergoes oxidative modification upon oxidative stress.In...
Glyceraldehyde-3-phosphate dehydrogenase is the enzyme responsible for converting glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate, a high-energy phosphate product. From:Free Radical Biology and Medicine,2007 About this page Add to MendeleySet alert ...
According to the results, compounds 1-12 interacted with the enzyme glyceraldehyde 3-phosphate dehydrogenase attractively, and the compounds coumarin-5, coumarin-2, tiliroside, and chalepin, have lower interaction energy, showing to be more stable in complexes with the active site of the enzyme (...
It catalyses the oxidative phosphorylation of glyceraldehyde-3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG), with NAD+ or NADP+ acting as a cofactor. The reaction is fully reversible, so BPG becomes the substrate and NAD(P)H the cofactor in gluconeogenesis (Fothergill-Gilmore LAMichels,...
Products Intro: Product Name:Glyceraldehyde-3-phosphate Dehydrogenase from Mouse, RecombinantPurity:> 95% by SDS-PAGE Remarks:Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis. It has also been shown to have ...
breakdown of glucose (glycolysis), an important pathway of energy and carbon molecule supply located in the cytosol of eukaryotic cells. Glyceraldehyde 3-phosphate is converted toD-glycerate 1,3-bisphosphatein two coupled steps. The first is favourable and allows the second unfavourable step to ...
Related to Glyceraldehyde phosphate dehydrogenase: G3PDHglyc·er·al·de·hyde (glĭs′ə-răl′də-hīd′) n. A sweet colorless crystalline solid, C3H6O3, that is an intermediate compound in carbohydrate metabolism. [glycer(in) + aldehyde.] American Heritage® Dictionary of the English ...
Top of pageREFERENCES The formation of binary complexes between sturgeon apoglyceraldehyde-3-phosphate dehydrogenase, coenzymes (NAD + and NADH) and substrates (phosphate, glyceraldehyde 3-phosphate and 1,3-bisphosphoglycerate) has been studied spectrophotometrically and spectrofluorometrically. Coenzyme bin...
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) catalyzes the conversion of D-glyceraldehyde 3-phosphate to D-glycerate 1,3-bisphosphate in the 6th critical step in glycolysis. GAPDH exerts metabolic flux control during aerobic glycolysis and therefore is an attractive therapeutic target for cancer and...
Identification and characterization of glyceraldehyde 3-phosphate dehydrogenase from Fasciola gigantica oxidative phosphorylation of d-glyceraldehyde-3-phosphate (G-3-P) to 1,3-bisphosphoglycerate (1,3-BPG), with the simultaneous reduction of NAD(+) to... RTT Chetri - 《Parasitology Research》 被引...