甘油醛-3-磷酸脱氢酶(Glyceraldehyde-3-Phosphate Dehydrogenase) 别名:GAPDH;3-磷酸甘油醛脱氢酶。分子式: C3H7O6P,分子量:170.0。应用:生化研究。 来源:from rabbit muscle 酶活定义:在pH7.6,25℃,3-磷酸甘油磷酸激酶存在条件下,每分钟将1.0μmol磷酸甘油醛还原为D-甘油醛-3-磷酸的酶量定义为一个酶活单位...
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes reversibly the oxidation and phosphorylation of D-glyceraldehyde 3-phosphate (G-3P) to 1,3-diphosphoglycerate (DPGA). Glyceraldehyde-3-phosphate dehydrogenase occurs widely and abundantly throughout nature. It comprises about 20% of the total ...
However, their mechanism of action is not clear, since the neuroprotective effect of MAO B inhibitors is associated with the blockage of glyceraldehyde-3-phosphate dehydrogenase (GAPDH)-death cascade, rather than the inhibition of MAO B. Here, we provide evidence that GAPDH potentiates the ethanol...
Glyceraldehyde 3-phosphate dehydrogenase. Simultaneous oxidation and phosphorylation of G3P produces 1,3-bispho- sphoglycerate (1,3-BPG) and NADH. Inorganic phosphate, rather than ATP, is used in this phosphorylation step. Phosphoglycerate kinase. Transfer of a phosphate from 1,3-BPG to AD...
Glaser PE, Han X, Gross RW: Tubulin is the endogenous inhibitor of the glyceraldehyde 3-phosphate dehydrogenase isoform that catalyzes membrane fusion: Implications for the coordinated regulation of glycolysis and membrane fusion. Proc Natl Acad Sci USA. 2002, 99: 14104-14109. 10.1073/pnas.2225429...
Glyceraldehyde-3-phosphate dehydrogenase GM-CSF: Granulocyte–macrophage colony-stimulating factor HDM: House dust mite HRP: Horseradish peroxidase i.n.: Intranasal i.p.: Intraperitoneal i.r.: Intrarectal IEF: Isoelectric focusing IFN-γ: Interferon-gamma IHC: Immunohistochemistry IL: ...
Huang Y., Zhang P., Yang Z., Wang P., Li H., Gao Z. Interaction of glyceraldehyde-3-phosphate dehydrogenase and heme: the relevance of its biological function Arch. Biochem. Biophys, 619 (2017), pp. 54-61 10.1016/j.abb.2017.03.005 28315300 View PDFView articleView in ScopusGoogle Sc...
Wang D, Moothart DR, Lowy DR, Qian X: The expression of glyceraldehyde-3-phosphate dehydrogenase associated cell cycle (gacc) genes correlates with cancer stage and poor survival in patients with solid tumors. PLoS One. 2013, 8: e61262- Article PubMed Central CAS PubMed Google Scholar Piero...
New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was considered a classical glycolytic protein examined for its pivotal role in energy production. It was a... MA Sirover - 《Biochimica Et...
THE enzymatic reaction catalysed by glyceraldehyde-3-phosphate dehydrogenase (GAPD) is thought to occur through the formation of an acyl-enzyme compound which involves some of the thiol groups of the enzyme 1–3 . Although the complex nature of enzyme reactions renders it improbable to attribute ...