Rather than increasing insulin secretion, chromium appears to improve glycaemic control by enhancing the action of insulin; improving the ability of insulin to bind to cells; enhancing beta-cell sensitivity; increasing the number of insulin receptors; and activating insulin receptor kinase, thus ...
The pathogenesis of type 2 diabetes is multifacted and involves both impaired insulin secretion and increased insulin resistance. The use of two oral antidiabetic agents with complementary mechanisms of action may result in a synergistic effect, resulting in a greater response than could be obtained...