Insulin glulisine has a faster onset of action compared with insulin aspart in healthy volunteers. Exp Clin Endocrinol Diabetes 2010; 118: 662-664.Arnolds S,Rave K,Hovelmann U,et al.Insulin glulisine has a faster onset of action compared with insulin aspart in healthy volunteers. Experimental...
These structural modifications decrease hexamer formation, stabilize insulin glulisine monomers and increase the rate of absorption and onset of action compared to human insulin. 药物别名 Insulin glulisine;Insulin Glulisine (recombinant DNA origin);Insulin glulisine recombinant;Insulina glulisina 治疗...
Insulin glulisine: a faster onset of action compared with insulin lispro Aim: This randomized, single-centre, double-blind, crossover study compared the pharmacodynamic and pharmacokinetic properties of two different doses of i... T Heise,L Nosek,H Spitzer,... - 《Diabetes Obesity & Metabolism...
Insulin glulisine (Apidra®) is a human insulin analogue approved for the improvement of glycaemic control in adults, adolescents and children with diabetes mellitus. It has similar binding properties, and is associated with a faster onset but similar level of glucose disposal, to regular human i...
Insulin glulisine is a rapid-acting human insulin analogue that has a faster onset of action and shorter duration of action than regular human insulin (RHI) in patients with type 1 or 2 diabetes mellitus and is efficacious in controlling prandial blood glucose levels in these patients. In ...
Heise T,Nosek L,Spitzer H,et al.Insulin glulisine:a faster onset of action compared with insulin lispro. Diabetes Obesity and Metabolism . 2007Heise T, Nosek L, Spitzer H, Heinemann L, Niemoller E, Frick AD, Becker RHA. Insulin glulisi- ne: a faster onset of action compared with ...
Compared with regular human insulin, glulisine has a more rapid onset of action and shorter duration of effect, affording greater flexibility in the timing and content of meals. Additionally, optional pre- or postmeal administration makes glulisine well suited for patients who eat erratically or ...
Subcutaneous administration of insulin glulisine has a faster subcutaneous absorption, a more rapid onset of activity, and a shorter duration of action than regular human insulin. These properties of insulin glulisine allow it to be administe...
Insulin glulisine (Apidra, Sanofi-Aventis), a new and recently approved rapid-acting insulin analogue, mimics the pharmacokinetic and pharmacodynamic profiles of physiological human insulin, but has a rapid onset, peak effect at 1h, and a shorter duration of action (approximately 4 h). Its rapid...
Insulin glulisine (Apidra, Sanofi-Aventis), a new and recently approved rapid-acting insulin analogue, mimics the pharmacokinetic and pharmacodynamic profiles of physiological human insulin, but has a rapid onset, peak effect at 1h, and a shorter duration of action (approximately 4 h). Its rapid...