We report here that glucose-regulated protein (GRP)-78, a critical regulator of the unfolded protein response (UPR), is a novel downstream target of BRCA1. We showed that overexpression of wild-type BRCA1 suppressed the expression of GRP78, whereas expression of mutant BRCA1 gene or targeted...
Here, we identified a novel MC4R-interacting protein, glucose-regulated protein 78 (GRP78), from a pulldown assay using hypothalamic protein extracts and the third intracellular loop of MC4R. We found that MC4R interacted with GRP78 in both the cytosol and at the cell surface and that this ...
Glucose-regulated protein 78 (GRP 78) is a heat shock 70-related protein that resides in the lumen of the endoplasmic reticulum (ER) which is involved in multimeric protein assembly, the degradation of proteins, and the storage and regulation of ER luminal calcium. ...
Glucose-regulated protein (GRP) 78 (also known as HSPA5 or BiP), is a member of the heat shock protein 70 (HSP70) family of proteins, which are involved in ER stress. GRP78 expression is induced during oxidative stress (Kitamura and Hiramatsu, 2010), chemical toxicity (Falahatpisheh et ...
Glucose-regulated protein 78 (GRP78) plays an essential role in embryonic development and in the progression and therapeutic resistance of many cancers. However, little is known about the function of GRP78 in hormone-independent prostate cancer. Here, we found that the expression levels of GRP...
深入研究「Silencing of glucose-regulated protein 78 (GRP78) enhances cell migration through the upregulation of vimentin in hepatocellular carcinoma cells」主題。共同形成了獨特的指紋。 Cell Migration Biochemistry, Genetics and Molecular Biology 100% Upregulation Biochemistry, Genetics and Molecul...
Glucose-Regulated Protein 78 (GRP78) is a chaperone protein that is predominantly expressed in the lumen of the endoplasmic reticulum. GRP78 plays a crucial role in protein folding by assisting in the assembly of misfolded proteins. Under cellular stress conditions, GRP78 can translocate to the ...
Glucose Regulated Protein 78 (Grp78, BiP) 供应商 MyBioSource 产品货号 MBS610773 产品报价 ￥询价/0.05mg ￥询价/0.2mg ￥询价/其它规格 产品说明书 点击查看 购买方式 MyBioSource中国区金牌代理,部分产品现货库存。银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868 ...
上海玉博生物科技有限公司 主要致力于“GRP78(glucose regulated protein 78) 葡萄糖调节蛋白78抗原(热休克蛋白70蛋白5) yb-1219P”的生产销售。多年的“GRP78(glucose regulated protein 78) 葡萄糖调节蛋白78抗原(热休克蛋白70蛋白5) yb-1219P”生产与销售的经
Benign prostatic hyperplasia (BPH) is a chronic condition which mainly affects elderly males. Existing scientific evidences have not completely revealed the pathogenesis of BPH. Glucose-regulated protein 78 (GRP78) is a member of the heat shock protein 7