Glucose is an important energy source for your brain and body. Your body converts carbohydrates and simple sugars in your diet to glucose for fuel usage. Your pancreas releases a hormone called insulin to regulate blood glucose levels. According to the American Diabetes Association, a normal fasti...
Results Blood glucose level, even when in high normal range, or in slightly high range is an important determinant of morbidity and mortality, especially in hospitalized patients. Even slight elevation of blood glucose may increase mortality in patients with COVID-19. Further, blood glucose ...
The median follow-up time and number of participants with first developed CVD were 7.0 years (interquartile range: 6.7–7.3) years and 1889, respectively, for index age 35 years. Corresponding values were 7.0 (6.6–7.3) years and 1790 for index age 45 years, and 6.9 (6.5–7.1) years ...
As a part of metabolic homeostasis, our body maintains blood glucose levels within a narrow range. The liver is responsible for maintaining normal blood glucose levels1. In an early fasting state, insulin mainly regulates blood glucose levels by inhibiting hepatic glucose production and glycogenolysis...
Second, glucose metabolism of cancer cells is different from normal cells mainly because of a lack of oxygen present in hypoxic tumour conditions. Activation of hypoxia-inducible factor stimulates the expression of glycolytic enzymes and decreases reliance on mitochondrial oxidative phosphorylation in ...
individuals who have impaired glucose tolerance diagnosed by an OGTT revert to normal glucose tolerance on retesting. Non-diabetic hyperglycaemia (NDH) is increasingly being used as a wider term that encompasses hyperglycaemia where the HbA1c level is raised but is below the diabetic range (Table ...
ACS is the most severe type of ischaemic heart disease and describes a range of myocardial ischaemic conditions, including unstable angina (UA), non-ST elevated myocardial infarction (NSTEMI), and ST-elevated myocardial infarction (STEMI) [30]. Despite the use of current guideline-recommended ther...
These results correspond to another trial with acute MI patients showing that HbA1c and proinsulin were in the lowest range in patients with normal glucose regulation, intermediate in patients with impaired glucose tolerance, and highest in patients with type 2 diabetes [25]. The present results ...
Hyperglycemia in type 2 diabetes mellitus has been linked to non-alcoholic fatty liver disease, which can progress to inflammation, fibrosis/cirrhosis and hepatocellular carcinoma. Understanding how chronic hyperglycemia affects primary human hepatocytes
Self-monitoring of blood glucose (SMBG) has been established as a valuable tool for the management of diabetes [6-12]. The goal of SMBG is to help the patient achieve and maintain normal blood glucose concentrations in order to delay or even prevent the progression of microvascular (...