来源期刊 Circulation journal : official journal of the Japanese Circulation Society 研究点推荐 High Blood Glucose Level 站内活动 0关于我们 百度学术集成海量学术资源,融合人工智能、深度学习、大数据分析等技术,为科研工作者提供全面快捷的学术服务。在这里我们保持学习的态度,不忘初心,砥砺前行。了解更多>>...
coli K-12 (JM109 and MG1655) did not respond to the high glucose concentration, and, therefore, transcription of sgrS was not detected and ptsG mRNA level was not affected. Conclusions The results suggest that E. coli B (BL21) tolerates high glucose concentration not only by its more ...
However, an elevated risk of amputation was detected in patients from both CANVAS studies, which were primarily at the level of the toe or metatarsal [104], in agreement with previous observations [105,106]. In this regard, a recent real-world retrospective cohort study in t...
FSH primarily acts on the gonads and regulates the reproductive processes. Although the conventional idea has been expanded by the discovery of functional FSHR in bone cells, adipocytes, hepatocytes, and neurons, previous studies only have focused on postmenopausal high FSH level related to bone loss...
(water) level of theory and transition-state structures (Carbon: gray, hydrogen: white, Oxygen: red, Nitrogen: blue, angles are shown in o, and distances are shown in Å). The WT is shown in the black line, while mutant Mu5 is shown in the red line.n = 3 independent ...
[127]. Enhanced fructose consumption, being the result of a Western diet, leads to elevated accumulation of saturated fatty acids and enhanced gluconeogenesis rates in the liver, eventually inducing liver steatosis. On a molecular level, increased fructose influx into hepatocytes stimulates the ...
Given the relatively low level of UDP-GalNAc, we did not separate UDP-GlcNAc and UDP-GalNAc in our experiments, and values are reported as UDP-GlcNAc rather than UDP-HexNAc (made up of both UDP-GlcNAc and UDP-GalNAc). Download: Download high-res image (123KB) Download: Download full-...
Despite all of this, the value of LODs by the HPLC-ELSD method is beyond 1 μg/mL except fructose in this study, and some compounds present in jujube extract with low level were not detected by the HPLC-ELSD method, such as rhamnose, xylitol and arabitol. Smaller values of LODs were ...
High intracellular glucose concentration leads to the exhaustion of the antioxidant pathways, altered regulation of gene transcription and increased expression of pro-inflammatory molecules resulting in cellular dysfunction and death65. On a clinical level, these cellular changes translate into micro and ...
It was therefore necessary to verify the expression of glucokinase at the single cell level in a pure alpha cell preparation. With our sorting protocol we obtained functional rat alpha cells with a high purity (96.6 ± 1.4%)16. To test which hexokinase isoforms are expressed in rat ...