ABI5encodes a transcription factor belonging to a large basic leucine zipper (bZIP) domain family and plays a crucial role in ABA signal transduction, especially during seed development and germination76,77,78,79. Theabi5-7mutant is originally discovered for its insensitivity to high level of exo...
hepaticglucose production, and peripheralglucose uptake(i.e., all processes contributing to the 2-h glucose value). Because of the high variability in the 2-h glucose value, a diagnosis of IGT or diabetes, particularly if intervention is planned, should not be based on a single OGTT. Instead...
At the same time, they also can be at high risk for hypoxia, hypotension, pneumothoraces, and hemodynamic abnormalities, which could predispose them to brain injury (10, 11). The findings of our study may be interpreted to suggest that prolonged exposures to moderate increases in plasma ...
It is a very high-affinity transporter for glucosamine (Km ~ 0.8 mM) [14, 19, 20]. GLUT2 is present in the hepatocytes, intestines (in the basolateral membrane of the epithelial cells), β-cells of pancreas [21], in a small number in neurons in the central nervous system, astrocytes...
Interestingly, the diabetes 2344 death rate in England decreased by approximately 55% between 1941 and 1954–1957, when low-fibre white flour was replaced by the wartime high-fibre national flour [10]. Acute effects of dietary fibres have been studied exten- sively, the focus of interest ...
Download: Download high-res image (127KB) Download: Download full-size image Fig. 2. Effect of caveolin-1 coexpression on maximal electrogenic glucose transport in SGLT1-expressing Xenopus oocytes. Arithmetic means ± SEM (n = 4–12) of glucose induced current (Ig) as a function of glucose...
Concern exists that increasing fructose consumption, particularly in the form of high-fructose corn syrup, is resulting in increasing rates of fructose int... ME Latulippe,SM Skoog - 《Crit Rev Food Sci Nutr》 被引量: 107发表: 2011年 ...
SGLT2 (Table1) is the major transporter responsible for the reabsorption of glucose from the glomerular filtrate back into the circulation, is characterized by low affinity, high volume, as well as is predominantly expressed in the proximal tubules [19,20]. By inhibiting SGLT2, SGLT2 inhibitors...
Modulating insulin secretion as a means of diabetes therapy Due to the worldwide, still spreading epidemic of T2DM, there is an urgent need for (new) anti-diabetic drugs and therapies that are more effective and have fewer side effects. Currently, the most commonly used drugs can be classified...
We demonstrate that the uptake of glucose- coated magnetic nanoparticles (MNPs) by mesenchymal-like cells remains constant when the glucose in the medium is increased from low (5.5 mM) to high (25 mM) concentration, while the MNPs uptake by epithelial-like cells is significantly reduced....