Conclusion: Our result suggested a negative association between TyG-BMI index and testosterone in adult males. The predictability of the TyG-BMI index for testosterone deficiency is better than that of HOMA-IR index and TyG index.Shenghao Wu...
摘要: Presents a study on the effects of negative arterial-portal venous glucose gradient on skeletal muscle and whole body nonhepatic glucose intake in 12 hour fasted conscious dogs. Mechanism of glucose production; Methodology; Results of the study....
Arabidopsis (Arabidopsis thaliana) Hexokinase-Like1 (HKL1) lacks glucose (Glc) phosphorylation activity and has been shown to act as a negative regulator of plant growth. Interestingly, the protein has a largely conserved Glc-binding domain, and protein overexpression was shown previously to promote...
This negative regulation leads to high levels of glycogen synthase activity during fasting conditions, which in turn increases substrate (futile) cycling, priming the system for a rapid response once an external source of glucose is restored. This work demonstrates that a mechanistic understanding of ...
Fig. 2: Demonstration of gene circuit-based sensors linked to a glucose output. aEffect of trehalose substrate concentration on glucose output levels in a blank CFS reaction (N, negative control), or reactions with toehold switch-regulated glucose production in the absence (S, switch only) or...
We found that physiological stimuli known to induce PGC-1alpha expression in skeletal muscle coordinately upregulate the expression of pyruvate dehydrogenase kinase 4 (PDK4), a negative regulator of glucose oxidation. Forced expression of PGC-1alpha in C(2)C(12) myotubes induced PDK4 mRNA and ...
Having observed that cysts expand under microfluidic conditions, it was important to establish a corresponding static condition lacking flow as a negative control. Initially we utilized the same chambers and syringe pump in the absence of pump activation, which is a commonly used control format for ...
(p = 0.0001); management distress (p = 0.0001); hypoglycemia distress (p = 0.0001); negative social perceptions (p = 0.0001); eating (p = 0.0001); physician distress (p = 0.0001); friend/family distress (p = 0.0001); and total T1-DDS score (p =...
leading to the inactivation of p53 function and suppressing the apoptosis10. A previous study reported that GRP75 positive tumors had a worse prognosis compared with GRP75 negative tumors in GC with normal p53 function11. However, p53 was one of the most frequently mutated genes in GC (affectin...
被引量: 2发表: 1984年 Structural determination of lipid A from gram negative bacteria using laser desorption mass spectrometry Laser desorption mass spectrometry has been employed for the structural determination of lipid A components derived from the lipopolysaccharides (LPS) of g... RJ Cotter,J Ho...