ThymidylyltransferaseEnzymecatalysischemicalThymidine2.7.7.24 dTTP:a-D-glucose- 1-phosphate thymidylyltransferase glucose-l-phosphate thymidylyltransferase TDP-glucose pyrophosphorylase dTDP-glucose synthase dTDP-glucose-pyrophosphorylase dTDPglucose py
In this study, we describe the direct synthesis of uridine 5-diphosphate galactose (UDP-Gal) by a wild-type bacterial thymidylyltransferase (RmlA), which is used to synthesize thymidine 5-diphosphate glucose (TDP-glucose) in nature. By using magnesium (Mg2+) as a cofactor and a reaction ...
专利名称：GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE AND METHOD FOR SELECTING INHIBITORS THEREOF 发明人：NAISMITH, James,BLANKENFELDT, Wulf 申请号：GB2001003152 申请日：20010713 公开号：WO02/006509P1 公开日：20020124 专利内容由知识产权出版社提供 摘要：There is provided a method of obtaining selecting ...
glucose-1-phosphate thymidylyltransferase 中文别名: CBNumber: CB11386494 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商2 glucose-1-phosphate thymidylyltransferase化学性质 安全信息 glucose-1-phosphate thymidylyltransferase性质、用途与生产工艺 ...
There is provided a method of obtaining selecting agents which inhibit the enzyme glucose-1-phosphate thymidylyltransferase (Rm1A) based upon analysis of a model of the active and regulatory site (s) of Rm1A and interaction therewith by a potential inhibitory agent. The invention is based upon...
英文名称:glucose-1-phosphate thymidylyltransferase 英文同义词:glucose-1-phosphate thymidylyltransferase CAS号:9026-03-3 分子式: 分子量:0 EINECS号: 信息错误报告 您的Email: 按国家浏览glucose-1-phosphate thymidylyltransferase国外供应商中国供应商 ...
The ligand lies across the mixed β-sheet of the core near β-strands 1 and 6. The cytosine base adopts the anti-conformation whereas the ribose assumes the C2′-endo pucker. In sharp contrast to the active sites of the glucose-1-phosphate thymidylyltransferases, in cytidylyltransferase the...
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3B) leading to a conformation of UTP similar to that of dTTP in the structurally related glucose-1-phosphate thymidylyltransferase (RmlA/RffH) (24, 25). Based on our structural data we mutated several substrate binding residues in the active site of UGPase to further study the importance ...
multiple mechanisms involved in the regulation of ADP-Glc PPase. The rational modification of this enzyme could improve the yield and resilience of economically important crops, which is particularly important in the current scenario of climate change and food shortage....